BACCHUS: A randomised non-comparative phase II study of neoadjuvant chemotherapy (NACT) in patients with locally advanced rectal cancer (LARC)

BACCHUS: A randomised non-comparative phase II study of neoadjuvant chemotherapy (NACT) in patients with locally advanced rectal cancer (LARC)

Background: Chemoradiation (CRT) or short-course radiotherapy (SCRT) are standard treatments for locally advanced rectal cancer (LARC). We evaluated the efficacy/safety of two neoadjuvant chemotherapy (NACT) regimens as an alternative prior to total mesorectal excision (TME). Methods/design: This mu...

Full description

Bibliographic Details
Main Authors: R. Glynne-Jones, M.R. Hall, A. Lopes, S. Pearce, V. Goh, S. Bosompem, J. Bridgewater, I. Chau, H. Wasan, B. Moran, L. Melcher, N.P. West, P. Quirke, W.-L. Wong, S. Beare, N. Hava, M. Duggan, M. Harrison
Format: Article
Language:English
Published: Elsevier 2018-09-01
Series:Heliyon
Subjects:
Oncology
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844018320590

Similar Items

Similar Items