Relation between Preoperative Mild Increased in Serum Creatinine Level and Early Outcomes after Coronary Artery Bypass Grafting
This study evaluates the effect of preoperative increased level of serum creatinine (Cr) on early outcomes after coronary artery bypass graft surgery (CABG). 1140 patients who underwent CABG in our center were studied. Patients with Cr >2.25 mg/dl or preoperative dialysis and who had off-pump ope...
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| Format: | Article |
| Language: | English |
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Tehran University of Medical Sciences
2011-02-01
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| Series: | Acta Medica Iranica |
| Subjects: | |
| Online Access: | https://acta.tums.ac.ir/index.php/acta/article/view/3699 |
| _version_ | 1811265874664882176 |
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| author | Hassan Radmehr Seyed Khalil Forouzannia Ali Reza Bakhshandeh Mehdi Sanatkar |
| author_facet | Hassan Radmehr Seyed Khalil Forouzannia Ali Reza Bakhshandeh Mehdi Sanatkar |
| author_sort | Hassan Radmehr |
| collection | DOAJ |
| description | This study evaluates the effect of preoperative increased level of serum creatinine (Cr) on early outcomes after coronary artery bypass graft surgery (CABG). 1140 patients who underwent CABG in our center were studied. Patients with Cr >2.25 mg/dl or preoperative dialysis and who had off-pump operations were excluded. Group 1 consisted of 892 patients with normal Cr (0.5-1.2 mg/dl) and group 2 consisted of 248 (21.8%) patients with mild increased level of serum Cr (1.3-2.2 mg/dl). Patients in group 1 were younger than group 2. There were more patients with hypertension in group 2, but there were not statistically significant difference between two groups in terms of the frequency of diabetes, smoking, cerebrovascular disease and New York Heart Association (NYHA) class. Left ventricular ejection fraction (LVEF) was lower in group 2. Cardiopulmonary bypass time (CPB) was longer in group 2. Early mortality was 3.2% in group 1 and 8.4% in group 2 (P<0.001). Prolonged ICU stay, low cardiac output, prolonged mechanical ventilation, postoperative atrial fibrillation, postoperative re-exploration and sepsis were more frequent in group 2. Mild increase in serum Cr level preoperatively is a marker of increased early mortality and outcome after CABG. |
| first_indexed | 2024-04-12T20:31:49Z |
| format | Article |
| id | doaj.art-b41ddbb2927947a3b7b8005f72785448 |
| institution | Directory Open Access Journal |
| issn | 0044-6025 1735-9694 |
| language | English |
| last_indexed | 2024-04-12T20:31:49Z |
| publishDate | 2011-02-01 |
| publisher | Tehran University of Medical Sciences |
| record_format | Article |
| series | Acta Medica Iranica |
| spelling | doaj.art-b41ddbb2927947a3b7b8005f727854482022-12-22T03:17:43ZengTehran University of Medical SciencesActa Medica Iranica0044-60251735-96942011-02-01492Relation between Preoperative Mild Increased in Serum Creatinine Level and Early Outcomes after Coronary Artery Bypass GraftingHassan Radmehr0Seyed Khalil Forouzannia1Ali Reza Bakhshandeh2Mehdi Sanatkar3Cardiovascular Surgery Department, Imam Khomeini Medical Center, Tehran University of Medical Sciences, Tehran, Iran.Cardiovascular Research Center, Afshar Hospital, Shahid Sadooghi University of Medical Sciences, Yazd, Iran.Cardiovascular Surgery Department, Imam Khomeini Medical Center, Tehran University of Medical Sciences, Tehran, Iran.Cardiovascular Surgery Department, Imam Khomeini Medical Center, Tehran University of Medical Sciences, Tehran, Iran.This study evaluates the effect of preoperative increased level of serum creatinine (Cr) on early outcomes after coronary artery bypass graft surgery (CABG). 1140 patients who underwent CABG in our center were studied. Patients with Cr >2.25 mg/dl or preoperative dialysis and who had off-pump operations were excluded. Group 1 consisted of 892 patients with normal Cr (0.5-1.2 mg/dl) and group 2 consisted of 248 (21.8%) patients with mild increased level of serum Cr (1.3-2.2 mg/dl). Patients in group 1 were younger than group 2. There were more patients with hypertension in group 2, but there were not statistically significant difference between two groups in terms of the frequency of diabetes, smoking, cerebrovascular disease and New York Heart Association (NYHA) class. Left ventricular ejection fraction (LVEF) was lower in group 2. Cardiopulmonary bypass time (CPB) was longer in group 2. Early mortality was 3.2% in group 1 and 8.4% in group 2 (P<0.001). Prolonged ICU stay, low cardiac output, prolonged mechanical ventilation, postoperative atrial fibrillation, postoperative re-exploration and sepsis were more frequent in group 2. Mild increase in serum Cr level preoperatively is a marker of increased early mortality and outcome after CABG.https://acta.tums.ac.ir/index.php/acta/article/view/3699Serum creatinineCoronary artery bypass graft surgeryEarly mortality |
| spellingShingle | Hassan Radmehr Seyed Khalil Forouzannia Ali Reza Bakhshandeh Mehdi Sanatkar Relation between Preoperative Mild Increased in Serum Creatinine Level and Early Outcomes after Coronary Artery Bypass Grafting Acta Medica Iranica Serum creatinine Coronary artery bypass graft surgery Early mortality |
| title | Relation between Preoperative Mild Increased in Serum Creatinine Level and Early Outcomes after Coronary Artery Bypass Grafting |
| title_full | Relation between Preoperative Mild Increased in Serum Creatinine Level and Early Outcomes after Coronary Artery Bypass Grafting |
| title_fullStr | Relation between Preoperative Mild Increased in Serum Creatinine Level and Early Outcomes after Coronary Artery Bypass Grafting |
| title_full_unstemmed | Relation between Preoperative Mild Increased in Serum Creatinine Level and Early Outcomes after Coronary Artery Bypass Grafting |
| title_short | Relation between Preoperative Mild Increased in Serum Creatinine Level and Early Outcomes after Coronary Artery Bypass Grafting |
| title_sort | relation between preoperative mild increased in serum creatinine level and early outcomes after coronary artery bypass grafting |
| topic | Serum creatinine Coronary artery bypass graft surgery Early mortality |
| url | https://acta.tums.ac.ir/index.php/acta/article/view/3699 |
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