Formyl peptide receptor type 2 (FPR2) deficiency in myeloid cells amplifies sepsis-induced cardiac dysfunction
Using a global formyl-peptide receptor (Fpr)2 knockout mouse colony, we have reported the modulatory properties of this pro-resolving receptor in polymicrobial sepsis. Herein, we have used a humanized FPR2 (hFPR2) mouse colony bearing an intact or a selective receptor deficiency in myeloid cells to...
Main Authors: | Jianmin Chen, Shani Austin-Williams, Caroline Elizabeth O'Riordan, Pol Claria-Ribas, Michelle A Sugimoto, Lucy V Norling, Christoph Thiemermann, Mauro Perretti |
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Format: | Article |
Language: | English |
Published: |
Karger Publishers
2023-04-01
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Series: | Journal of Innate Immunity |
Online Access: | https://www.karger.com/Article/FullText/530284 |
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