Formyl peptide receptor type 2 (FPR2) deficiency in myeloid cells amplifies sepsis-induced cardiac dysfunction

Using a global formyl-peptide receptor (Fpr)2 knockout mouse colony, we have reported the modulatory properties of this pro-resolving receptor in polymicrobial sepsis. Herein, we have used a humanized FPR2 (hFPR2) mouse colony bearing an intact or a selective receptor deficiency in myeloid cells to...

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Bibliographic Details
Main Authors: Jianmin Chen, Shani Austin-Williams, Caroline Elizabeth O'Riordan, Pol Claria-Ribas, Michelle A Sugimoto, Lucy V Norling, Christoph Thiemermann, Mauro Perretti
Format: Article
Language:English
Published: Karger Publishers 2023-04-01
Series:Journal of Innate Immunity
Online Access:https://www.karger.com/Article/FullText/530284

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