Epistasis studies reveal redundancy among calcium-dependent protein kinases in motility and invasion of malaria parasites
Despite functional optimisation during evolution of parasitism, most members of a calcium dependent protein kinase (CDPK) family show genetic redundancy in Plasmodium. Here, the authors screen 294 genetic interactions among protein kinases in Plasmodium and show how some CDPKs functionally interact...
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Bibliographic Details
| Main Authors: |
Hanwei Fang,
Ana Rita Gomes,
Natacha Klages,
Paco Pino,
Bohumil Maco,
Eloise M. Walker,
Zenon A. Zenonos,
Fiona Angrisano,
Jake Baum,
Christian Doerig,
David A. Baker,
Oliver Billker,
Mathieu Brochet |
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| Format: | Article
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| Language: | English |
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| Published: |
Nature Portfolio
2018-10-01
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| Series: | Nature Communications
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| Online Access: | https://doi.org/10.1038/s41467-018-06733-w
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