Exosomes: Their Role in Pathogenesis, Diagnosis and Treatment of Diseases
Exosomes are lipid bilayer particles released from cells into their surrounding environment. These vesicles are mediators of near and long-distance intercellular communication and affect various aspects of cell biology. In addition to their biological function, they play an increasingly important ro...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2020-12-01
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| Series: | Cancers |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2072-6694/13/1/84 |
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| author | Houssam Aheget Loubna Mazini Francisco Martin Boutaïna Belqat Juan Antonio Marchal Karim Benabdellah |
| author_facet | Houssam Aheget Loubna Mazini Francisco Martin Boutaïna Belqat Juan Antonio Marchal Karim Benabdellah |
| author_sort | Houssam Aheget |
| collection | DOAJ |
| description | Exosomes are lipid bilayer particles released from cells into their surrounding environment. These vesicles are mediators of near and long-distance intercellular communication and affect various aspects of cell biology. In addition to their biological function, they play an increasingly important role both in diagnosis and as therapeutic agents. In this paper, we review recent literature related to the molecular composition of exosomes, paying special attention to their role in pathogenesis, along with their application as biomarkers and as therapeutic tools. In this context, we analyze the potential use of exosomes in biomedicine, as well as the limitations that preclude their wider application. |
| first_indexed | 2024-03-10T13:39:58Z |
| format | Article |
| id | doaj.art-b427cdee530f4772a657ad3845839f8e |
| institution | Directory Open Access Journal |
| issn | 2072-6694 |
| language | English |
| last_indexed | 2024-03-10T13:39:58Z |
| publishDate | 2020-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Cancers |
| spelling | doaj.art-b427cdee530f4772a657ad3845839f8e2023-11-21T03:06:58ZengMDPI AGCancers2072-66942020-12-011318410.3390/cancers13010084Exosomes: Their Role in Pathogenesis, Diagnosis and Treatment of DiseasesHoussam Aheget0Loubna Mazini1Francisco Martin2Boutaïna Belqat3Juan Antonio Marchal4Karim Benabdellah5GENYO Centre for Genomics and Oncological Research, Genomic Medicine Department, Pfizer/University of Granada/Andalusian Regional Government, Health Sciences Technology Park, Av. de la Illustration 114, 18016 Granada, SpainCenter of Biological and Medical Sciences (CIAM), Mohammed VI Polytechnic University, Ben-Guerir 43152, MoroccoGENYO Centre for Genomics and Oncological Research, Genomic Medicine Department, Pfizer/University of Granada/Andalusian Regional Government, Health Sciences Technology Park, Av. de la Illustration 114, 18016 Granada, SpainDepartment of Biology, Faculty of Sciences, University Abdelmalek Essaâdi, Tétouan 93000, MoroccoBiomedical Research Institute (ibs. GRANADA), 18012 Granada, SpainGENYO Centre for Genomics and Oncological Research, Genomic Medicine Department, Pfizer/University of Granada/Andalusian Regional Government, Health Sciences Technology Park, Av. de la Illustration 114, 18016 Granada, SpainExosomes are lipid bilayer particles released from cells into their surrounding environment. These vesicles are mediators of near and long-distance intercellular communication and affect various aspects of cell biology. In addition to their biological function, they play an increasingly important role both in diagnosis and as therapeutic agents. In this paper, we review recent literature related to the molecular composition of exosomes, paying special attention to their role in pathogenesis, along with their application as biomarkers and as therapeutic tools. In this context, we analyze the potential use of exosomes in biomedicine, as well as the limitations that preclude their wider application.https://www.mdpi.com/2072-6694/13/1/84exosomesmolecular compositioncancer pathogenesisdiagnosticstherapeutics |
| spellingShingle | Houssam Aheget Loubna Mazini Francisco Martin Boutaïna Belqat Juan Antonio Marchal Karim Benabdellah Exosomes: Their Role in Pathogenesis, Diagnosis and Treatment of Diseases Cancers exosomes molecular composition cancer pathogenesis diagnostics therapeutics |
| title | Exosomes: Their Role in Pathogenesis, Diagnosis and Treatment of Diseases |
| title_full | Exosomes: Their Role in Pathogenesis, Diagnosis and Treatment of Diseases |
| title_fullStr | Exosomes: Their Role in Pathogenesis, Diagnosis and Treatment of Diseases |
| title_full_unstemmed | Exosomes: Their Role in Pathogenesis, Diagnosis and Treatment of Diseases |
| title_short | Exosomes: Their Role in Pathogenesis, Diagnosis and Treatment of Diseases |
| title_sort | exosomes their role in pathogenesis diagnosis and treatment of diseases |
| topic | exosomes molecular composition cancer pathogenesis diagnostics therapeutics |
| url | https://www.mdpi.com/2072-6694/13/1/84 |
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