Applications of soft biomaterials based on organic and hybrid thin films deposited from the vapor phase

Soft biomaterials are a crucial component in several application fields. They are used, for example, in biomedical implants, biosensors, drug delivery systems as well as in tissue engineering. In parallel to extensive ongoing efforts to synthesize new materials, the development of means to tailor th...

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Main Authors: Sophie Marcelja, Lisanne Demelius, Taher Abu Ali, Margherita Aghito, Fabian Muralter, Gabriel Hernandez Rodriguez, Marianne Kräuter, Katrin Unger, Lukas Wolfsberger, Anna Maria Coclite
Format: Article
Language:English
Published: IOP Publishing 2023-01-01
Series:JPhys Materials
Subjects:
Online Access:https://doi.org/10.1088/2515-7639/ace5df
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author Sophie Marcelja
Lisanne Demelius
Taher Abu Ali
Margherita Aghito
Fabian Muralter
Gabriel Hernandez Rodriguez
Marianne Kräuter
Katrin Unger
Lukas Wolfsberger
Anna Maria Coclite
author_facet Sophie Marcelja
Lisanne Demelius
Taher Abu Ali
Margherita Aghito
Fabian Muralter
Gabriel Hernandez Rodriguez
Marianne Kräuter
Katrin Unger
Lukas Wolfsberger
Anna Maria Coclite
author_sort Sophie Marcelja
collection DOAJ
description Soft biomaterials are a crucial component in several application fields. They are used, for example, in biomedical implants, biosensors, drug delivery systems as well as in tissue engineering. In parallel to extensive ongoing efforts to synthesize new materials, the development of means to tailor the materials’ surface properties and thus their interaction with the environment is an important field of research. This has led to the emergence of several surface modification techniques that enable the exploitation of biomaterials in a broader range of technologies. In particular, the use of functional thin films can enable a plethora of biomedical applications by combining advantageous bulk properties of the substrate (e.g. flexibility, lightweight, structural strength) with tailored surface properties of the thin film (e.g. enhancing/prevention of cell proliferation, controlled drug release). For some biomedical applications, thin films can also be the main functional components, e.g. in biosensors. The present review focuses on recent developments in the applications of soft biomaterials based on thin films deposited from the vapor phase. In the field of soft biomaterials, the possibility of depositing from the vapor phase—without the need for any solvents—offers the unprecedented benefit that no toxic leachables are included in the biomaterial. Further, due to the complete lack of solvents and chemicals overall being used in small quantities only, depositing thin films from the vapor phase can be a more sustainable choice than other techniques that are commonly used.
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spelling doaj.art-b428fde233044be8a10d12fb6a94c6022023-08-08T09:38:51ZengIOP PublishingJPhys Materials2515-76392023-01-016404200110.1088/2515-7639/ace5dfApplications of soft biomaterials based on organic and hybrid thin films deposited from the vapor phaseSophie Marcelja0Lisanne Demelius1https://orcid.org/0000-0002-3013-2229Taher Abu Ali2https://orcid.org/0000-0003-0335-8588Margherita Aghito3Fabian Muralter4https://orcid.org/0000-0001-8038-6019Gabriel Hernandez Rodriguez5Marianne Kräuter6https://orcid.org/0000-0002-4925-6432Katrin Unger7https://orcid.org/0000-0003-0395-5411Lukas Wolfsberger8Anna Maria Coclite9https://orcid.org/0000-0001-5562-9744Institute of Solid State Physics, NAWI Graz, Graz University of Technology , Petersgasse 16, 8010 Graz, AustriaInstitute of Solid State Physics, NAWI Graz, Graz University of Technology , Petersgasse 16, 8010 Graz, AustriaInstitute of Solid State Physics, NAWI Graz, Graz University of Technology , Petersgasse 16, 8010 Graz, AustriaInstitute of Solid State Physics, NAWI Graz, Graz University of Technology , Petersgasse 16, 8010 Graz, AustriaInstitute of Solid State Physics, NAWI Graz, Graz University of Technology , Petersgasse 16, 8010 Graz, AustriaInstitute of Solid State Physics, NAWI Graz, Graz University of Technology , Petersgasse 16, 8010 Graz, AustriaInstitute of Solid State Physics, NAWI Graz, Graz University of Technology , Petersgasse 16, 8010 Graz, AustriaInstitute of Solid State Physics, NAWI Graz, Graz University of Technology , Petersgasse 16, 8010 Graz, Austria; Electronic Sensors, Silicon Austria Labs GmbH , 8010 Graz, AustriaInstitute of Solid State Physics, NAWI Graz, Graz University of Technology , Petersgasse 16, 8010 Graz, AustriaInstitute of Solid State Physics, NAWI Graz, Graz University of Technology , Petersgasse 16, 8010 Graz, AustriaSoft biomaterials are a crucial component in several application fields. They are used, for example, in biomedical implants, biosensors, drug delivery systems as well as in tissue engineering. In parallel to extensive ongoing efforts to synthesize new materials, the development of means to tailor the materials’ surface properties and thus their interaction with the environment is an important field of research. This has led to the emergence of several surface modification techniques that enable the exploitation of biomaterials in a broader range of technologies. In particular, the use of functional thin films can enable a plethora of biomedical applications by combining advantageous bulk properties of the substrate (e.g. flexibility, lightweight, structural strength) with tailored surface properties of the thin film (e.g. enhancing/prevention of cell proliferation, controlled drug release). For some biomedical applications, thin films can also be the main functional components, e.g. in biosensors. The present review focuses on recent developments in the applications of soft biomaterials based on thin films deposited from the vapor phase. In the field of soft biomaterials, the possibility of depositing from the vapor phase—without the need for any solvents—offers the unprecedented benefit that no toxic leachables are included in the biomaterial. Further, due to the complete lack of solvents and chemicals overall being used in small quantities only, depositing thin films from the vapor phase can be a more sustainable choice than other techniques that are commonly used.https://doi.org/10.1088/2515-7639/ace5dfthin filmsmembranessurface modificationvapor depositionsoft biomaterials
spellingShingle Sophie Marcelja
Lisanne Demelius
Taher Abu Ali
Margherita Aghito
Fabian Muralter
Gabriel Hernandez Rodriguez
Marianne Kräuter
Katrin Unger
Lukas Wolfsberger
Anna Maria Coclite
Applications of soft biomaterials based on organic and hybrid thin films deposited from the vapor phase
JPhys Materials
thin films
membranes
surface modification
vapor deposition
soft biomaterials
title Applications of soft biomaterials based on organic and hybrid thin films deposited from the vapor phase
title_full Applications of soft biomaterials based on organic and hybrid thin films deposited from the vapor phase
title_fullStr Applications of soft biomaterials based on organic and hybrid thin films deposited from the vapor phase
title_full_unstemmed Applications of soft biomaterials based on organic and hybrid thin films deposited from the vapor phase
title_short Applications of soft biomaterials based on organic and hybrid thin films deposited from the vapor phase
title_sort applications of soft biomaterials based on organic and hybrid thin films deposited from the vapor phase
topic thin films
membranes
surface modification
vapor deposition
soft biomaterials
url https://doi.org/10.1088/2515-7639/ace5df
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