Renal recovery following orthotopic liver transplant after prolonged kidney injury: Perspectives on diagnosing hepatorenal syndrome and determining which patients should undergo simultaneous liver kidney transplantation
We present a case of an individual with cirrhosis and renal failure. This case is notable because the patient was found to have hepatorenal syndrome (HRS) superimposed on Immunoglobulin A (IgA) nephropathy. After 8 months of dialysis, the patient had significant renal recovery following orthotopic l...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Codon Publications
2017-07-01
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| Series: | Journal of Renal and Hepatic Disorders |
| Subjects: | |
| Online Access: | https://jrenhep.com/index.php/jrenhep/article/view/20 |
| _version_ | 1811245923804643328 |
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| author | Mary Elizabeth Card Gilbert Moeckel Jeffrey Michael Turner |
| author_facet | Mary Elizabeth Card Gilbert Moeckel Jeffrey Michael Turner |
| author_sort | Mary Elizabeth Card |
| collection | DOAJ |
| description | We present a case of an individual with cirrhosis and renal failure. This case is notable because the patient was found to have hepatorenal syndrome (HRS) superimposed on Immunoglobulin A (IgA) nephropathy. After 8 months of dialysis, the patient had significant renal recovery following orthotopic liver transplant (OLT). Cases such as this are not likely to be rare, as case series have shown that IgA deposits are a common occurrence in patients with cirrhosis, including those who have HRS. While current diagnostic criteria for HRS emphasize the importance of excluding glomerular lesions, we argue that this approach should be reconsidered. More specifically, we feel that the diagnostic approach to HRS should be more inclusive of cases in which patients have simultaneous HRS and glomerular injury. In addition, our case highlights the challenges in determining which patients will benefit most from simultaneous liver–kidney transplants over OLTs alone. |
| first_indexed | 2024-04-12T14:46:21Z |
| format | Article |
| id | doaj.art-b42a42c732dd4dbbbb5cd021e9dc5af4 |
| institution | Directory Open Access Journal |
| issn | 2207-3744 |
| language | English |
| last_indexed | 2024-04-12T14:46:21Z |
| publishDate | 2017-07-01 |
| publisher | Codon Publications |
| record_format | Article |
| series | Journal of Renal and Hepatic Disorders |
| spelling | doaj.art-b42a42c732dd4dbbbb5cd021e9dc5af42022-12-22T03:28:38ZengCodon PublicationsJournal of Renal and Hepatic Disorders2207-37442017-07-011210.15586/jrenhep.2017.2013Renal recovery following orthotopic liver transplant after prolonged kidney injury: Perspectives on diagnosing hepatorenal syndrome and determining which patients should undergo simultaneous liver kidney transplantationMary Elizabeth Card0Gilbert Moeckel1Jeffrey Michael Turner2Department of Internal Medicine, Yale School of Medicine, New Haven CT, USADepartment of Pathology, Yale School of Medicine, New Haven, CT, USADepartment of Internal Medicine, Yale School of Medicine, New Haven CT, USAWe present a case of an individual with cirrhosis and renal failure. This case is notable because the patient was found to have hepatorenal syndrome (HRS) superimposed on Immunoglobulin A (IgA) nephropathy. After 8 months of dialysis, the patient had significant renal recovery following orthotopic liver transplant (OLT). Cases such as this are not likely to be rare, as case series have shown that IgA deposits are a common occurrence in patients with cirrhosis, including those who have HRS. While current diagnostic criteria for HRS emphasize the importance of excluding glomerular lesions, we argue that this approach should be reconsidered. More specifically, we feel that the diagnostic approach to HRS should be more inclusive of cases in which patients have simultaneous HRS and glomerular injury. In addition, our case highlights the challenges in determining which patients will benefit most from simultaneous liver–kidney transplants over OLTs alone.https://jrenhep.com/index.php/jrenhep/article/view/20hepatorenal syndromesimultaneously liver kidney transplantIgA Nephropathyothrotopic liver transplant |
| spellingShingle | Mary Elizabeth Card Gilbert Moeckel Jeffrey Michael Turner Renal recovery following orthotopic liver transplant after prolonged kidney injury: Perspectives on diagnosing hepatorenal syndrome and determining which patients should undergo simultaneous liver kidney transplantation Journal of Renal and Hepatic Disorders hepatorenal syndrome simultaneously liver kidney transplant IgA Nephropathy othrotopic liver transplant |
| title | Renal recovery following orthotopic liver transplant after prolonged kidney injury: Perspectives on diagnosing hepatorenal syndrome and determining which patients should undergo simultaneous liver kidney transplantation |
| title_full | Renal recovery following orthotopic liver transplant after prolonged kidney injury: Perspectives on diagnosing hepatorenal syndrome and determining which patients should undergo simultaneous liver kidney transplantation |
| title_fullStr | Renal recovery following orthotopic liver transplant after prolonged kidney injury: Perspectives on diagnosing hepatorenal syndrome and determining which patients should undergo simultaneous liver kidney transplantation |
| title_full_unstemmed | Renal recovery following orthotopic liver transplant after prolonged kidney injury: Perspectives on diagnosing hepatorenal syndrome and determining which patients should undergo simultaneous liver kidney transplantation |
| title_short | Renal recovery following orthotopic liver transplant after prolonged kidney injury: Perspectives on diagnosing hepatorenal syndrome and determining which patients should undergo simultaneous liver kidney transplantation |
| title_sort | renal recovery following orthotopic liver transplant after prolonged kidney injury perspectives on diagnosing hepatorenal syndrome and determining which patients should undergo simultaneous liver kidney transplantation |
| topic | hepatorenal syndrome simultaneously liver kidney transplant IgA Nephropathy othrotopic liver transplant |
| url | https://jrenhep.com/index.php/jrenhep/article/view/20 |
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