Prevalence of Iron deficiency anemia in children with liver cirrhosis: A cross-sectional study
Background: Among the many complications reported for cirrhosis, iron deficiency anemia (IDA) has attracted much attention. This type of anemia, in contrast to other types of anemia, is easy to treat prophylactically, but if left untreated can lead to a poor quality of life. The aim of this study wa...
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| Format: | Article |
| Language: | English |
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Tehran University of Medical Sciences
2015-09-01
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| Series: | International Journal of Hematology-Oncology and Stem Cell Research |
| Subjects: | |
| Online Access: | https://ijhoscr.tums.ac.ir/index.php/ijhoscr/article/view/383 |
| _version_ | 1827852475049181184 |
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| author | Soheila Zareifar Seyed Mohsen Dehghani Najmeh Rahanjam Mohammad Reza Farahmand Far |
| author_facet | Soheila Zareifar Seyed Mohsen Dehghani Najmeh Rahanjam Mohammad Reza Farahmand Far |
| author_sort | Soheila Zareifar |
| collection | DOAJ |
| description | Background: Among the many complications reported for cirrhosis, iron deficiency anemia (IDA) has attracted much attention. This type of anemia, in contrast to other types of anemia, is easy to treat prophylactically, but if left untreated can lead to a poor quality of life. The aim of this study was to estimate the hemoglobin and serum iron levels among patients with liver cirrhosis for the early diagnosis of IDA and to avoid unnecessary testing and iron supplementation.
Subjects and Methods: In this cross-sectional study, 88 children diagnosed with cirrhosis were included, and the values of hemoglobin, serum iron levels and relationship between serum iron (SI), total iron-binding capacity (TIBC), prothrombine time (PT), international normalization ratio (INR), total and direct bilirubin and hepatic enzymes were estimated using paired t test, Mann-Whitney, Chi-square and Kruskal-Wallis tests.
Results: Forty-six (52.3%) of 88 children were girls and 42 (47.7%) were boys. Forty-eight (54.5%) patients had anemia and 8 (9%) had iron deficiency anemia (5 boys, 5.6%, and 3 girls, 3.4%). No relationships were observed between iron deficiency anemia and the patient’s age or gender, whereas there was a relationship between iron deficiency and severity and duration of the disease, although the correlation was not statistically significant.
Conclusion: The high frequency of iron deficiency anemia in children with cirrhosis (9%) suggests that timely screening should be used for early diagnosis and treatment. |
| first_indexed | 2024-03-12T10:50:50Z |
| format | Article |
| id | doaj.art-b42a4e8d8e1e47ea9551ca46e5ab6f84 |
| institution | Directory Open Access Journal |
| issn | 2008-2207 |
| language | English |
| last_indexed | 2024-03-12T10:50:50Z |
| publishDate | 2015-09-01 |
| publisher | Tehran University of Medical Sciences |
| record_format | Article |
| series | International Journal of Hematology-Oncology and Stem Cell Research |
| spelling | doaj.art-b42a4e8d8e1e47ea9551ca46e5ab6f842023-09-02T07:03:15ZengTehran University of Medical SciencesInternational Journal of Hematology-Oncology and Stem Cell Research2008-22072015-09-0193369Prevalence of Iron deficiency anemia in children with liver cirrhosis: A cross-sectional studySoheila Zareifar0Seyed Mohsen Dehghani1Najmeh Rahanjam2Mohammad Reza Farahmand Far3Pediatric Hematology and Oncology Department, Shiraz University of Medical Sciences, Shiraz, Iran.Gasteroenterology Department, Shiraz University of Medical Sciences, Shiraz, Iran.Pediatric Hematology and Oncology Department, Shiraz University of Medical Sciences, Shiraz, Iran.Pediatric Hematology and Oncology Department, Shiraz University of Medical Sciences, Shiraz, Iran.Background: Among the many complications reported for cirrhosis, iron deficiency anemia (IDA) has attracted much attention. This type of anemia, in contrast to other types of anemia, is easy to treat prophylactically, but if left untreated can lead to a poor quality of life. The aim of this study was to estimate the hemoglobin and serum iron levels among patients with liver cirrhosis for the early diagnosis of IDA and to avoid unnecessary testing and iron supplementation. Subjects and Methods: In this cross-sectional study, 88 children diagnosed with cirrhosis were included, and the values of hemoglobin, serum iron levels and relationship between serum iron (SI), total iron-binding capacity (TIBC), prothrombine time (PT), international normalization ratio (INR), total and direct bilirubin and hepatic enzymes were estimated using paired t test, Mann-Whitney, Chi-square and Kruskal-Wallis tests. Results: Forty-six (52.3%) of 88 children were girls and 42 (47.7%) were boys. Forty-eight (54.5%) patients had anemia and 8 (9%) had iron deficiency anemia (5 boys, 5.6%, and 3 girls, 3.4%). No relationships were observed between iron deficiency anemia and the patient’s age or gender, whereas there was a relationship between iron deficiency and severity and duration of the disease, although the correlation was not statistically significant. Conclusion: The high frequency of iron deficiency anemia in children with cirrhosis (9%) suggests that timely screening should be used for early diagnosis and treatment.https://ijhoscr.tums.ac.ir/index.php/ijhoscr/article/view/383ChildrenCirrhosisIron deficiency anemia |
| spellingShingle | Soheila Zareifar Seyed Mohsen Dehghani Najmeh Rahanjam Mohammad Reza Farahmand Far Prevalence of Iron deficiency anemia in children with liver cirrhosis: A cross-sectional study International Journal of Hematology-Oncology and Stem Cell Research Children Cirrhosis Iron deficiency anemia |
| title | Prevalence of Iron deficiency anemia in children with liver cirrhosis: A cross-sectional study |
| title_full | Prevalence of Iron deficiency anemia in children with liver cirrhosis: A cross-sectional study |
| title_fullStr | Prevalence of Iron deficiency anemia in children with liver cirrhosis: A cross-sectional study |
| title_full_unstemmed | Prevalence of Iron deficiency anemia in children with liver cirrhosis: A cross-sectional study |
| title_short | Prevalence of Iron deficiency anemia in children with liver cirrhosis: A cross-sectional study |
| title_sort | prevalence of iron deficiency anemia in children with liver cirrhosis a cross sectional study |
| topic | Children Cirrhosis Iron deficiency anemia |
| url | https://ijhoscr.tums.ac.ir/index.php/ijhoscr/article/view/383 |
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