The Impact of Follicular Fluid Oxidative Stress Levels on the Outcomes of Assisted Reproductive Therapy
Oocyte quality is a pivotal determinant of assisted reproductive outcomes. The quality of oocytes is intricately linked to their developmental microenvironment, particularly the levels of oxidative stress within the follicular fluid. Oxidative stress levels in follicular fluid may have a substantial...
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MDPI AG
2023-12-01
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Series: | Antioxidants |
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Online Access: | https://www.mdpi.com/2076-3921/12/12/2117 |
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author | Yu Chen Jiahao Yang Ling Zhang |
author_facet | Yu Chen Jiahao Yang Ling Zhang |
author_sort | Yu Chen |
collection | DOAJ |
description | Oocyte quality is a pivotal determinant of assisted reproductive outcomes. The quality of oocytes is intricately linked to their developmental microenvironment, particularly the levels of oxidative stress within the follicular fluid. Oxidative stress levels in follicular fluid may have a substantial influence on oocyte health, thereby impacting the outcomes of ART procedures. This review meticulously explores the intricate relationship between oxidative stress in follicular fluid and ART outcomes. Furthermore, it delves into strategies aimed at ameliorating the oxidative stress status of follicular fluid, with the overarching goal of enhancing the overall efficacy of ART. This research endeavors to establish a robust foundation and provide valuable guidance for clinical treatment approaches, particularly in the context of infertile women, including those of advanced maternal age. |
first_indexed | 2024-03-08T21:02:52Z |
format | Article |
id | doaj.art-b42b51f76819496f966d2eab2999a24a |
institution | Directory Open Access Journal |
issn | 2076-3921 |
language | English |
last_indexed | 2024-03-08T21:02:52Z |
publishDate | 2023-12-01 |
publisher | MDPI AG |
record_format | Article |
series | Antioxidants |
spelling | doaj.art-b42b51f76819496f966d2eab2999a24a2023-12-22T13:48:36ZengMDPI AGAntioxidants2076-39212023-12-011212211710.3390/antiox12122117The Impact of Follicular Fluid Oxidative Stress Levels on the Outcomes of Assisted Reproductive TherapyYu Chen0Jiahao Yang1Ling Zhang2Institute of Reproductive Health, Tongji Medical College, Huazhong University of Science and Technology, No. 13 Hangkong Road, Wuhan 430030, ChinaInstitute of Reproductive Health, Tongji Medical College, Huazhong University of Science and Technology, No. 13 Hangkong Road, Wuhan 430030, ChinaInstitute of Reproductive Health, Tongji Medical College, Huazhong University of Science and Technology, No. 13 Hangkong Road, Wuhan 430030, ChinaOocyte quality is a pivotal determinant of assisted reproductive outcomes. The quality of oocytes is intricately linked to their developmental microenvironment, particularly the levels of oxidative stress within the follicular fluid. Oxidative stress levels in follicular fluid may have a substantial influence on oocyte health, thereby impacting the outcomes of ART procedures. This review meticulously explores the intricate relationship between oxidative stress in follicular fluid and ART outcomes. Furthermore, it delves into strategies aimed at ameliorating the oxidative stress status of follicular fluid, with the overarching goal of enhancing the overall efficacy of ART. This research endeavors to establish a robust foundation and provide valuable guidance for clinical treatment approaches, particularly in the context of infertile women, including those of advanced maternal age.https://www.mdpi.com/2076-3921/12/12/2117oxidative stressfollicular fluidassisted reproductive technology |
spellingShingle | Yu Chen Jiahao Yang Ling Zhang The Impact of Follicular Fluid Oxidative Stress Levels on the Outcomes of Assisted Reproductive Therapy Antioxidants oxidative stress follicular fluid assisted reproductive technology |
title | The Impact of Follicular Fluid Oxidative Stress Levels on the Outcomes of Assisted Reproductive Therapy |
title_full | The Impact of Follicular Fluid Oxidative Stress Levels on the Outcomes of Assisted Reproductive Therapy |
title_fullStr | The Impact of Follicular Fluid Oxidative Stress Levels on the Outcomes of Assisted Reproductive Therapy |
title_full_unstemmed | The Impact of Follicular Fluid Oxidative Stress Levels on the Outcomes of Assisted Reproductive Therapy |
title_short | The Impact of Follicular Fluid Oxidative Stress Levels on the Outcomes of Assisted Reproductive Therapy |
title_sort | impact of follicular fluid oxidative stress levels on the outcomes of assisted reproductive therapy |
topic | oxidative stress follicular fluid assisted reproductive technology |
url | https://www.mdpi.com/2076-3921/12/12/2117 |
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