The Impact of Follicular Fluid Oxidative Stress Levels on the Outcomes of Assisted Reproductive Therapy

Oocyte quality is a pivotal determinant of assisted reproductive outcomes. The quality of oocytes is intricately linked to their developmental microenvironment, particularly the levels of oxidative stress within the follicular fluid. Oxidative stress levels in follicular fluid may have a substantial...

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Main Authors: Yu Chen, Jiahao Yang, Ling Zhang
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Antioxidants
Subjects:
Online Access:https://www.mdpi.com/2076-3921/12/12/2117
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author Yu Chen
Jiahao Yang
Ling Zhang
author_facet Yu Chen
Jiahao Yang
Ling Zhang
author_sort Yu Chen
collection DOAJ
description Oocyte quality is a pivotal determinant of assisted reproductive outcomes. The quality of oocytes is intricately linked to their developmental microenvironment, particularly the levels of oxidative stress within the follicular fluid. Oxidative stress levels in follicular fluid may have a substantial influence on oocyte health, thereby impacting the outcomes of ART procedures. This review meticulously explores the intricate relationship between oxidative stress in follicular fluid and ART outcomes. Furthermore, it delves into strategies aimed at ameliorating the oxidative stress status of follicular fluid, with the overarching goal of enhancing the overall efficacy of ART. This research endeavors to establish a robust foundation and provide valuable guidance for clinical treatment approaches, particularly in the context of infertile women, including those of advanced maternal age.
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spelling doaj.art-b42b51f76819496f966d2eab2999a24a2023-12-22T13:48:36ZengMDPI AGAntioxidants2076-39212023-12-011212211710.3390/antiox12122117The Impact of Follicular Fluid Oxidative Stress Levels on the Outcomes of Assisted Reproductive TherapyYu Chen0Jiahao Yang1Ling Zhang2Institute of Reproductive Health, Tongji Medical College, Huazhong University of Science and Technology, No. 13 Hangkong Road, Wuhan 430030, ChinaInstitute of Reproductive Health, Tongji Medical College, Huazhong University of Science and Technology, No. 13 Hangkong Road, Wuhan 430030, ChinaInstitute of Reproductive Health, Tongji Medical College, Huazhong University of Science and Technology, No. 13 Hangkong Road, Wuhan 430030, ChinaOocyte quality is a pivotal determinant of assisted reproductive outcomes. The quality of oocytes is intricately linked to their developmental microenvironment, particularly the levels of oxidative stress within the follicular fluid. Oxidative stress levels in follicular fluid may have a substantial influence on oocyte health, thereby impacting the outcomes of ART procedures. This review meticulously explores the intricate relationship between oxidative stress in follicular fluid and ART outcomes. Furthermore, it delves into strategies aimed at ameliorating the oxidative stress status of follicular fluid, with the overarching goal of enhancing the overall efficacy of ART. This research endeavors to establish a robust foundation and provide valuable guidance for clinical treatment approaches, particularly in the context of infertile women, including those of advanced maternal age.https://www.mdpi.com/2076-3921/12/12/2117oxidative stressfollicular fluidassisted reproductive technology
spellingShingle Yu Chen
Jiahao Yang
Ling Zhang
The Impact of Follicular Fluid Oxidative Stress Levels on the Outcomes of Assisted Reproductive Therapy
Antioxidants
oxidative stress
follicular fluid
assisted reproductive technology
title The Impact of Follicular Fluid Oxidative Stress Levels on the Outcomes of Assisted Reproductive Therapy
title_full The Impact of Follicular Fluid Oxidative Stress Levels on the Outcomes of Assisted Reproductive Therapy
title_fullStr The Impact of Follicular Fluid Oxidative Stress Levels on the Outcomes of Assisted Reproductive Therapy
title_full_unstemmed The Impact of Follicular Fluid Oxidative Stress Levels on the Outcomes of Assisted Reproductive Therapy
title_short The Impact of Follicular Fluid Oxidative Stress Levels on the Outcomes of Assisted Reproductive Therapy
title_sort impact of follicular fluid oxidative stress levels on the outcomes of assisted reproductive therapy
topic oxidative stress
follicular fluid
assisted reproductive technology
url https://www.mdpi.com/2076-3921/12/12/2117
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