DGPathinter: a novel model for identifying driver genes via knowledge-driven matrix factorization with prior knowledge from interactome and pathways
Cataloging mutated driver genes that confer a selective growth advantage for tumor cells from sporadic passenger mutations is a critical problem in cancer genomic research. Previous studies have reported that some driver genes are not highly frequently mutated and cannot be tested as statistically s...
Main Authors: | Jianing Xi, Minghui Wang, Ao Li |
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Format: | Article |
Language: | English |
Published: |
PeerJ Inc.
2017-10-01
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Series: | PeerJ Computer Science |
Subjects: | |
Online Access: | https://peerj.com/articles/cs-133.pdf |
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