Isoquinoline Alkaloids in Sows’ Diet Reduce Body Weight Loss during Lactation and Increase IgG in Colostrum
Isoquinoline alkaloids (IQ) exert beneficial antimicrobial and anti-inflammatory effects in livestock. Therefore, we hypothesized that supplementing sows’ diets with IQ during gestation would decrease farrowing stress, affecting the piglets’ development and performance. Sows were divided into: IQ1,...
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MDPI AG
2021-07-01
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| Series: | Animals |
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| Online Access: | https://www.mdpi.com/2076-2615/11/8/2195 |
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| author | Ester Arévalo Sureda Xuemei Zhao Valeria Artuso-Ponte Sophie-Charlotte Wall Bing Li Wei Fang Julie Uerlings Yuping Zhang Martine Schroyen Clément Grelet Frédéric Dehareng José Wavreille Nadia Everaert |
| author_facet | Ester Arévalo Sureda Xuemei Zhao Valeria Artuso-Ponte Sophie-Charlotte Wall Bing Li Wei Fang Julie Uerlings Yuping Zhang Martine Schroyen Clément Grelet Frédéric Dehareng José Wavreille Nadia Everaert |
| author_sort | Ester Arévalo Sureda |
| collection | DOAJ |
| description | Isoquinoline alkaloids (IQ) exert beneficial antimicrobial and anti-inflammatory effects in livestock. Therefore, we hypothesized that supplementing sows’ diets with IQ during gestation would decrease farrowing stress, affecting the piglets’ development and performance. Sows were divided into: IQ1, supplemented with IQ from gestation day 80 (G80) to weaning; IQ2, supplemented from gestation day 110 (G110) to weaning, and a non-supplemented (NC) group. Sow body weight (BW), feed intake, back-fat thickness and back-muscle thickness were monitored. Cortisol, glucose and insulin were measured in sows’ blood collected 5 d before, during, and after 7 d farrowing. Protein, fat, IgA and IgG were analyzed in the colostrum and milk. Piglets were monitored for weight and diarrhea score, and for ileum histology and gene expression 5 d post-weaning. IQ-supplemented sows lost less BW during lactation. Glucose and insulin levels were lower in the IQ groups compared to NC-sows 5 d before farrowing and had higher levels of protein and IgG in their colostrum. No other differences were observed in sows, nor in the measured parameters in piglets. In conclusion, IQ supplementation affected sows’ metabolism, reducing body weight loss during lactation. Providing IQ to sows from their entrance into the maternity barn might be sufficient to induce these effects. IQ improved colostrum quality, increasing the protein and IgG content, improving passive immunity for piglets. |
| first_indexed | 2024-03-10T09:05:33Z |
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| institution | Directory Open Access Journal |
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| language | English |
| last_indexed | 2024-03-10T09:05:33Z |
| publishDate | 2021-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Animals |
| spelling | doaj.art-b42d3de58ef4446daf8e48a0e398ac382023-11-22T06:28:35ZengMDPI AGAnimals2076-26152021-07-01118219510.3390/ani11082195Isoquinoline Alkaloids in Sows’ Diet Reduce Body Weight Loss during Lactation and Increase IgG in ColostrumEster Arévalo Sureda0Xuemei Zhao1Valeria Artuso-Ponte2Sophie-Charlotte Wall3Bing Li4Wei Fang5Julie Uerlings6Yuping Zhang7Martine Schroyen8Clément Grelet9Frédéric Dehareng10José Wavreille11Nadia Everaert12Precision Livestock and Nutrition Laboratory, TERRA Teaching and Research Centre, GeQAmbloux Agro-Bio Tech, University of Liège, 5030 Gembloux, BelgiumPrecision Livestock and Nutrition Laboratory, TERRA Teaching and Research Centre, GeQAmbloux Agro-Bio Tech, University of Liège, 5030 Gembloux, BelgiumPhytobiotics Futterzusatzstoffe GmbH, 65343 Eltville, GermanyPhytobiotics Futterzusatzstoffe GmbH, 65343 Eltville, GermanyPrecision Livestock and Nutrition Laboratory, TERRA Teaching and Research Centre, GeQAmbloux Agro-Bio Tech, University of Liège, 5030 Gembloux, BelgiumPrecision Livestock and Nutrition Laboratory, TERRA Teaching and Research Centre, GeQAmbloux Agro-Bio Tech, University of Liège, 5030 Gembloux, BelgiumPrecision Livestock and Nutrition Laboratory, TERRA Teaching and Research Centre, GeQAmbloux Agro-Bio Tech, University of Liège, 5030 Gembloux, BelgiumPrecision Livestock and Nutrition Laboratory, TERRA Teaching and Research Centre, GeQAmbloux Agro-Bio Tech, University of Liège, 5030 Gembloux, BelgiumPrecision Livestock and Nutrition Laboratory, TERRA Teaching and Research Centre, GeQAmbloux Agro-Bio Tech, University of Liège, 5030 Gembloux, BelgiumValorisation of Agricultural Products Department, Walloon Agricultural Research Centre, 5030 Gembloux, BelgiumValorisation of Agricultural Products Department, Walloon Agricultural Research Centre, 5030 Gembloux, BelgiumProduction and Sectors Department, Walloon Agricultural Research Centre, 5030 Gembloux, BelgiumPrecision Livestock and Nutrition Laboratory, TERRA Teaching and Research Centre, GeQAmbloux Agro-Bio Tech, University of Liège, 5030 Gembloux, BelgiumIsoquinoline alkaloids (IQ) exert beneficial antimicrobial and anti-inflammatory effects in livestock. Therefore, we hypothesized that supplementing sows’ diets with IQ during gestation would decrease farrowing stress, affecting the piglets’ development and performance. Sows were divided into: IQ1, supplemented with IQ from gestation day 80 (G80) to weaning; IQ2, supplemented from gestation day 110 (G110) to weaning, and a non-supplemented (NC) group. Sow body weight (BW), feed intake, back-fat thickness and back-muscle thickness were monitored. Cortisol, glucose and insulin were measured in sows’ blood collected 5 d before, during, and after 7 d farrowing. Protein, fat, IgA and IgG were analyzed in the colostrum and milk. Piglets were monitored for weight and diarrhea score, and for ileum histology and gene expression 5 d post-weaning. IQ-supplemented sows lost less BW during lactation. Glucose and insulin levels were lower in the IQ groups compared to NC-sows 5 d before farrowing and had higher levels of protein and IgG in their colostrum. No other differences were observed in sows, nor in the measured parameters in piglets. In conclusion, IQ supplementation affected sows’ metabolism, reducing body weight loss during lactation. Providing IQ to sows from their entrance into the maternity barn might be sufficient to induce these effects. IQ improved colostrum quality, increasing the protein and IgG content, improving passive immunity for piglets.https://www.mdpi.com/2076-2615/11/8/2195farrowing stressmaternal programmingpigletscolostrumgrowth performance |
| spellingShingle | Ester Arévalo Sureda Xuemei Zhao Valeria Artuso-Ponte Sophie-Charlotte Wall Bing Li Wei Fang Julie Uerlings Yuping Zhang Martine Schroyen Clément Grelet Frédéric Dehareng José Wavreille Nadia Everaert Isoquinoline Alkaloids in Sows’ Diet Reduce Body Weight Loss during Lactation and Increase IgG in Colostrum Animals farrowing stress maternal programming piglets colostrum growth performance |
| title | Isoquinoline Alkaloids in Sows’ Diet Reduce Body Weight Loss during Lactation and Increase IgG in Colostrum |
| title_full | Isoquinoline Alkaloids in Sows’ Diet Reduce Body Weight Loss during Lactation and Increase IgG in Colostrum |
| title_fullStr | Isoquinoline Alkaloids in Sows’ Diet Reduce Body Weight Loss during Lactation and Increase IgG in Colostrum |
| title_full_unstemmed | Isoquinoline Alkaloids in Sows’ Diet Reduce Body Weight Loss during Lactation and Increase IgG in Colostrum |
| title_short | Isoquinoline Alkaloids in Sows’ Diet Reduce Body Weight Loss during Lactation and Increase IgG in Colostrum |
| title_sort | isoquinoline alkaloids in sows diet reduce body weight loss during lactation and increase igg in colostrum |
| topic | farrowing stress maternal programming piglets colostrum growth performance |
| url | https://www.mdpi.com/2076-2615/11/8/2195 |
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