Opsoclonus myoclonus syndrome in a patient with Japanese encephalitis: a case report
Abstract Background Opsoclonus myoclonus syndrome is a rare neurological disorder that usually manifests as a paraneoplastic phenomenon. Although some viruses are reported to cause this condition, opsoclonus myoclonus syndrome by Japanese encephalitis has not been reported previously. Case presentat...
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| Format: | Article |
| Language: | English |
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BMC
2017-10-01
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| Series: | Journal of Medical Case Reports |
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| Online Access: | http://link.springer.com/article/10.1186/s13256-017-1454-5 |
| _version_ | 1818875171134504960 |
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| author | Subatharshini Sountharalingam H. M. M. T. B. Herath Dharshana Wijegunasinghe Sunethra Senanayke |
| author_facet | Subatharshini Sountharalingam H. M. M. T. B. Herath Dharshana Wijegunasinghe Sunethra Senanayke |
| author_sort | Subatharshini Sountharalingam |
| collection | DOAJ |
| description | Abstract Background Opsoclonus myoclonus syndrome is a rare neurological disorder that usually manifests as a paraneoplastic phenomenon. Although some viruses are reported to cause this condition, opsoclonus myoclonus syndrome by Japanese encephalitis has not been reported previously. Case presentation Here we present the case of a 31-year-old Sri Lankan woman who presented with fever, altered level of consciousness, opsoclonus, and facial myoclonus. She was diagnosed as having Japanese encephalitis based on cerebrospinal fluid and serum Japanese encephalitis-specific immunoglobulin M antibody and characteristic magnetic resonance imaging abnormalities. She was given intravenously administered methylprednisolone pulses (1000 mg per day) for 5 days. With this she improved gradually with reduction in opsoclonus and myoclonic movements. Her limb muscle power and speech also improved slowly. Conclusions We intended to highlight the fact that opsoclonus myoclonus syndrome can be a feature of infection with Japanese encephalitis and that it can be added to the list of viruses which cause opsoclonus. Currently there is no well-accepted treatment for opsoclonus myoclonus syndrome and intravenously administered methylprednisolone pulses and immunosuppressants can be used successfully in these patients for early recovery. |
| first_indexed | 2024-12-19T13:22:15Z |
| format | Article |
| id | doaj.art-b42ea5073fa5470a8c8dc6589225cdc6 |
| institution | Directory Open Access Journal |
| issn | 1752-1947 |
| language | English |
| last_indexed | 2024-12-19T13:22:15Z |
| publishDate | 2017-10-01 |
| publisher | BMC |
| record_format | Article |
| series | Journal of Medical Case Reports |
| spelling | doaj.art-b42ea5073fa5470a8c8dc6589225cdc62022-12-21T20:19:40ZengBMCJournal of Medical Case Reports1752-19472017-10-011111410.1186/s13256-017-1454-5Opsoclonus myoclonus syndrome in a patient with Japanese encephalitis: a case reportSubatharshini Sountharalingam0H. M. M. T. B. Herath1Dharshana Wijegunasinghe2Sunethra Senanayke3Medical Department, National Hospital of Sri LankaMedical Department, National Hospital of Sri LankaNeurology Department, National Hospital of Sri LankaNeurology Department, National Hospital of Sri LankaAbstract Background Opsoclonus myoclonus syndrome is a rare neurological disorder that usually manifests as a paraneoplastic phenomenon. Although some viruses are reported to cause this condition, opsoclonus myoclonus syndrome by Japanese encephalitis has not been reported previously. Case presentation Here we present the case of a 31-year-old Sri Lankan woman who presented with fever, altered level of consciousness, opsoclonus, and facial myoclonus. She was diagnosed as having Japanese encephalitis based on cerebrospinal fluid and serum Japanese encephalitis-specific immunoglobulin M antibody and characteristic magnetic resonance imaging abnormalities. She was given intravenously administered methylprednisolone pulses (1000 mg per day) for 5 days. With this she improved gradually with reduction in opsoclonus and myoclonic movements. Her limb muscle power and speech also improved slowly. Conclusions We intended to highlight the fact that opsoclonus myoclonus syndrome can be a feature of infection with Japanese encephalitis and that it can be added to the list of viruses which cause opsoclonus. Currently there is no well-accepted treatment for opsoclonus myoclonus syndrome and intravenously administered methylprednisolone pulses and immunosuppressants can be used successfully in these patients for early recovery.http://link.springer.com/article/10.1186/s13256-017-1454-5Japanese encephalitisOpsoclonus myoclonus syndrome |
| spellingShingle | Subatharshini Sountharalingam H. M. M. T. B. Herath Dharshana Wijegunasinghe Sunethra Senanayke Opsoclonus myoclonus syndrome in a patient with Japanese encephalitis: a case report Journal of Medical Case Reports Japanese encephalitis Opsoclonus myoclonus syndrome |
| title | Opsoclonus myoclonus syndrome in a patient with Japanese encephalitis: a case report |
| title_full | Opsoclonus myoclonus syndrome in a patient with Japanese encephalitis: a case report |
| title_fullStr | Opsoclonus myoclonus syndrome in a patient with Japanese encephalitis: a case report |
| title_full_unstemmed | Opsoclonus myoclonus syndrome in a patient with Japanese encephalitis: a case report |
| title_short | Opsoclonus myoclonus syndrome in a patient with Japanese encephalitis: a case report |
| title_sort | opsoclonus myoclonus syndrome in a patient with japanese encephalitis a case report |
| topic | Japanese encephalitis Opsoclonus myoclonus syndrome |
| url | http://link.springer.com/article/10.1186/s13256-017-1454-5 |
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