Surgical intervention in aggressive ulcerative pyoderma gangrenosum

Pyoderma Gangrenosum (PG) is a rare, debilitating, and painful disease of the skin. Its aetiology and pathophysiology are not well understood. However, it is known that PG is not bacterial in origin, as previously believed. A significant number of cases of PG report a phenomenon called pathergy, wh...

Full description

Bibliographic Details
Main Authors: Maham Mudassir, Rabia Ali, Sikandar Saeed, Ali Rafique Mirza
Format: Article
Language:English
Published: Pakistan Medical Association 2022-05-01
Series:Journal of the Pakistan Medical Association
Online Access:https://www.ojs.jpma.org.pk/index.php/public_html/article/view/1109
_version_ 1797820882323767296
author Maham Mudassir
Rabia Ali
Sikandar Saeed
Ali Rafique Mirza
author_facet Maham Mudassir
Rabia Ali
Sikandar Saeed
Ali Rafique Mirza
author_sort Maham Mudassir
collection DOAJ
description Pyoderma Gangrenosum (PG) is a rare, debilitating, and painful disease of the skin. Its aetiology and pathophysiology are not well understood. However, it is known that PG is not bacterial in origin, as previously believed. A significant number of cases of PG report a phenomenon called pathergy, which is characterized by the appearance of new lesions after the application of trauma to the skin. This represents a unique challenge for surgeons in cases that are refractory to medical therapy. The objective of this study is to review past literature and report a case of PG in a 19-year old woman, who presented with recurrence, after undergoing skin grafting one year back. The patient was referred for split thickness skin grafting (STSG) to reduce the psychological and physical morbidity as a result of this disease. Continuous...
first_indexed 2024-03-13T09:44:47Z
format Article
id doaj.art-b4323ebb6b3d4ebd899930ef58b78a54
institution Directory Open Access Journal
issn 0030-9982
language English
last_indexed 2024-03-13T09:44:47Z
publishDate 2022-05-01
publisher Pakistan Medical Association
record_format Article
series Journal of the Pakistan Medical Association
spelling doaj.art-b4323ebb6b3d4ebd899930ef58b78a542023-05-25T04:22:13ZengPakistan Medical AssociationJournal of the Pakistan Medical Association0030-99822022-05-01720110.47391/JPMA.11-1109Surgical intervention in aggressive ulcerative pyoderma gangrenosumMaham Mudassir0Rabia Ali1Sikandar Saeed2Ali Rafique Mirza3Department of Plastic Surgery, Shaikh Zayed Hospital, Lahore, Pakistan5th Year MBBS Student, Shifa College of Medicine, Islamabad, Pakistan5th Year MBBS Student, Shifa College of Medicine, Islamabad, PakistanDepartment of Plastic Surgery, Shaikh Zayed Hospital, Lahore, Pakistan Pyoderma Gangrenosum (PG) is a rare, debilitating, and painful disease of the skin. Its aetiology and pathophysiology are not well understood. However, it is known that PG is not bacterial in origin, as previously believed. A significant number of cases of PG report a phenomenon called pathergy, which is characterized by the appearance of new lesions after the application of trauma to the skin. This represents a unique challenge for surgeons in cases that are refractory to medical therapy. The objective of this study is to review past literature and report a case of PG in a 19-year old woman, who presented with recurrence, after undergoing skin grafting one year back. The patient was referred for split thickness skin grafting (STSG) to reduce the psychological and physical morbidity as a result of this disease. Continuous... https://www.ojs.jpma.org.pk/index.php/public_html/article/view/1109
spellingShingle Maham Mudassir
Rabia Ali
Sikandar Saeed
Ali Rafique Mirza
Surgical intervention in aggressive ulcerative pyoderma gangrenosum
Journal of the Pakistan Medical Association
title Surgical intervention in aggressive ulcerative pyoderma gangrenosum
title_full Surgical intervention in aggressive ulcerative pyoderma gangrenosum
title_fullStr Surgical intervention in aggressive ulcerative pyoderma gangrenosum
title_full_unstemmed Surgical intervention in aggressive ulcerative pyoderma gangrenosum
title_short Surgical intervention in aggressive ulcerative pyoderma gangrenosum
title_sort surgical intervention in aggressive ulcerative pyoderma gangrenosum
url https://www.ojs.jpma.org.pk/index.php/public_html/article/view/1109
work_keys_str_mv AT mahammudassir surgicalinterventioninaggressiveulcerativepyodermagangrenosum
AT rabiaali surgicalinterventioninaggressiveulcerativepyodermagangrenosum
AT sikandarsaeed surgicalinterventioninaggressiveulcerativepyodermagangrenosum
AT alirafiquemirza surgicalinterventioninaggressiveulcerativepyodermagangrenosum