Effect of Ginger on primary Dysmenorrhea: A systematic review of clinical trials and Quasi- Experimental studies in the world

Introduction: Dysmenorrhea is a common gynecological disorder that causes behavioral problems and impairment in daily life of a woman in each menstruation cycle. Ginger plays an effective role in treatment of dysmenorrhea. Therefore, this review article was performed with aim to collect and review t...

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Main Authors: Shabnam Mozafari, Marzieh Saei Ghare Naz, Giti Ozgoli
Format: Article
Language:fas
Published: Mashhad University of Medical Sciences 2018-08-01
Series:Majallah-i Zanān, Māmā̓ī va Nāzā̓ī-i Īrān
Subjects:
Online Access:https://ijogi.mums.ac.ir/article_11624_53195e5ae07fe89e28e70e3723b47a9d.pdf
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author Shabnam Mozafari
Marzieh Saei Ghare Naz
Giti Ozgoli
author_facet Shabnam Mozafari
Marzieh Saei Ghare Naz
Giti Ozgoli
author_sort Shabnam Mozafari
collection DOAJ
description Introduction: Dysmenorrhea is a common gynecological disorder that causes behavioral problems and impairment in daily life of a woman in each menstruation cycle. Ginger plays an effective role in treatment of dysmenorrhea. Therefore, this review article was performed with aim to collect and review the clinical trials about effects of oral and topical ginger on dysmenorrhea. Methods: In this review study, clinical trials and Quasi – Experimental studies up to Dec 2017 in Persian and English languages in Persian databases of IranMedex, Magiran, IranDoct, IRCT and English dataases of PubMed, Scopus, Science direct, Embase, Cochrane with  Persian and English keywords such as Dysmenorrhea, Menstrual pain, Menstrual cramps, Painful menstruation, Zingiber, Ginger, Shokyo, Gingiber officinale, and Zingier were reviewed without any time limitation and the articles with inclusion criteria entered into the study and were evaluated by qualitative analysis. Results: After reviewing 2101 articles, 12 clinical trials which based on Jadad score obtained ≥3 and 3 Quasi- experimental studies which based on EPHPP tool obtained 1.51-3.00 were evaluated. Most of the articles referred to the anti-inflammatory properties and inhibition of cyclooxygenase, followed by the reduction of gastrointestinal leukotriene and prostaglandin in relieving painful dysmenorrhea in both forms of oral and typical. There was not possible to do meta-analysis due to the heterogeneity of the studies. Conclusion: According to the results, there is credible evidence on the positive effect of oral and topical ginger on reducing pain and inflammation, especially in the first three days of menstruation.
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spelling doaj.art-b439b6cfc55a4ced96018ab113ca4c762022-12-22T04:38:23ZfasMashhad University of Medical SciencesMajallah-i Zanān, Māmā̓ī va Nāzā̓ī-i Īrān1680-29932008-23632018-08-0121ویژه نامه869310.22038/ijogi.2018.1162411624Effect of Ginger on primary Dysmenorrhea: A systematic review of clinical trials and Quasi- Experimental studies in the worldShabnam Mozafari0Marzieh Saei Ghare Naz1Giti Ozgoli2M.Sc. Student of Midwifery, Student Research Committee, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran.Ph.D. student in Reproductive Health, Student Research Committee, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran.Assistant professor, Department of Midwifery and Reproductive Health, Midwifery and Reproductive Health Research Center, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran.Introduction: Dysmenorrhea is a common gynecological disorder that causes behavioral problems and impairment in daily life of a woman in each menstruation cycle. Ginger plays an effective role in treatment of dysmenorrhea. Therefore, this review article was performed with aim to collect and review the clinical trials about effects of oral and topical ginger on dysmenorrhea. Methods: In this review study, clinical trials and Quasi – Experimental studies up to Dec 2017 in Persian and English languages in Persian databases of IranMedex, Magiran, IranDoct, IRCT and English dataases of PubMed, Scopus, Science direct, Embase, Cochrane with  Persian and English keywords such as Dysmenorrhea, Menstrual pain, Menstrual cramps, Painful menstruation, Zingiber, Ginger, Shokyo, Gingiber officinale, and Zingier were reviewed without any time limitation and the articles with inclusion criteria entered into the study and were evaluated by qualitative analysis. Results: After reviewing 2101 articles, 12 clinical trials which based on Jadad score obtained ≥3 and 3 Quasi- experimental studies which based on EPHPP tool obtained 1.51-3.00 were evaluated. Most of the articles referred to the anti-inflammatory properties and inhibition of cyclooxygenase, followed by the reduction of gastrointestinal leukotriene and prostaglandin in relieving painful dysmenorrhea in both forms of oral and typical. There was not possible to do meta-analysis due to the heterogeneity of the studies. Conclusion: According to the results, there is credible evidence on the positive effect of oral and topical ginger on reducing pain and inflammation, especially in the first three days of menstruation.https://ijogi.mums.ac.ir/article_11624_53195e5ae07fe89e28e70e3723b47a9d.pdfclinical trialdysmenorrheagingerherbal medicinepainful menstruation
spellingShingle Shabnam Mozafari
Marzieh Saei Ghare Naz
Giti Ozgoli
Effect of Ginger on primary Dysmenorrhea: A systematic review of clinical trials and Quasi- Experimental studies in the world
Majallah-i Zanān, Māmā̓ī va Nāzā̓ī-i Īrān
clinical trial
dysmenorrhea
ginger
herbal medicine
painful menstruation
title Effect of Ginger on primary Dysmenorrhea: A systematic review of clinical trials and Quasi- Experimental studies in the world
title_full Effect of Ginger on primary Dysmenorrhea: A systematic review of clinical trials and Quasi- Experimental studies in the world
title_fullStr Effect of Ginger on primary Dysmenorrhea: A systematic review of clinical trials and Quasi- Experimental studies in the world
title_full_unstemmed Effect of Ginger on primary Dysmenorrhea: A systematic review of clinical trials and Quasi- Experimental studies in the world
title_short Effect of Ginger on primary Dysmenorrhea: A systematic review of clinical trials and Quasi- Experimental studies in the world
title_sort effect of ginger on primary dysmenorrhea a systematic review of clinical trials and quasi experimental studies in the world
topic clinical trial
dysmenorrhea
ginger
herbal medicine
painful menstruation
url https://ijogi.mums.ac.ir/article_11624_53195e5ae07fe89e28e70e3723b47a9d.pdf
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