Role of Na+/Ca2+ Exchangers in Therapy Resistance of Medulloblastoma Cells

Role of Na+/Ca2+ Exchangers in Therapy Resistance of Medulloblastoma Cells

Background/Aims: Alterations of cytosolic Ca2+-activity ([Ca2+]i) are decisive in the regulation of tumor cell proliferation, migration and survival. Transport processes participating in the regulation of [Ca2+]i include Ca2+ extrusion through K+-independent (NCX) and/or K+-dependent (NCKX) Na+/Ca2+...

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Main Authors: Lisann Pelzl, Zohreh Hosseinzadeh, Tamer al-Maghout, Yogesh Singh, Itishri Sahu, Rosi Bissinger, Sebastian Schmidt, Saad Alkahtani, Christos Stournaras, Mahmoud Toulany, Florian Lang
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2017-07-01
Series:Cellular Physiology and Biochemistry
Subjects:
NCX3
NCKX2
NCKX5
Ionizing radiation
Apoptosis
Online Access:http://www.karger.com/Article/FullText/478953

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