Sonoporation using microbubbles promotes lipofectamine -mediated siRNA transduction to rat retina.

Sonoporation using microbubbles promotes lipofectamine -mediated siRNA transduction to rat retina.

Ultrasound-targeted microbubble destruction(UTMD) has been utilized to deliver naked siRNA into cells in in vitro settings. But whether UTMD can safely deliver naked siRNA into in vivo cells have remained unknown. This work was performed to investigate the feasibility of UTMD-enhanced naked siRNA t...

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Bibliographic Details
Main Authors: Xiaozhi Zheng, Ping Ji, Jianqun Hu
Format: Article
Language:English
Published: Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina 2011-08-01
Series:Biomolecules & Biomedicine
Subjects:
retina
ultrasound-targeted microbubble destruction
Lipofectamine 2000
siRNA
Online Access:https://www.bjbms.org/ojs/index.php/bjbms/article/view/2565

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