Acute posterior multifocal placoid pigment epitheliopathy (APMPPE)

Abstract Background Acute posterior multifocal placoid pigment epitheliopathy (APMPPE) is a rare inflammatory eye disease, affecting the inner choroid and the outer retina. Recent advances in multimodal imaging have been important in the understanding of the pathophysiology of the disease, allowing...

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Main Authors: Ilaria Testi, Sandra Vermeirsch, Carlos Pavesio
Format: Article
Language:English
Published: SpringerOpen 2021-11-01
Series:Journal of Ophthalmic Inflammation and Infection
Subjects:
Online Access:https://doi.org/10.1186/s12348-021-00263-1
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author Ilaria Testi
Sandra Vermeirsch
Carlos Pavesio
author_facet Ilaria Testi
Sandra Vermeirsch
Carlos Pavesio
author_sort Ilaria Testi
collection DOAJ
description Abstract Background Acute posterior multifocal placoid pigment epitheliopathy (APMPPE) is a rare inflammatory eye disease, affecting the inner choroid and the outer retina. Recent advances in multimodal imaging have been important in the understanding of the pathophysiology of the disease, allowing a better characterization of the morphology of this condition. Methods Narrative review. Results In this review, a comprehensive overview of clinical features, imaging findings, treatment management, and long-term outcomes of patients with APMPPE will be provided. Conclusions Although APMPPE was originally believed to be a self-limited condition with a good prognosis, the disease can be recurrent and result in significant loss of vision function. Fundus imaging plays an important role in the diagnosis and management of the disease, allowing to evaluate response to treatment and onset of complications.
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spelling doaj.art-b4430fd14e894cb3ba395a4b44ab71cb2022-12-21T18:42:05ZengSpringerOpenJournal of Ophthalmic Inflammation and Infection1869-57602021-11-011111810.1186/s12348-021-00263-1Acute posterior multifocal placoid pigment epitheliopathy (APMPPE)Ilaria Testi0Sandra Vermeirsch1Carlos Pavesio2Department of Uveitis, Moorfields Eye Hospital, National Health Service Foundation TrustDepartment of Uveitis, Moorfields Eye Hospital, National Health Service Foundation TrustDepartment of Uveitis, Moorfields Eye Hospital, National Health Service Foundation TrustAbstract Background Acute posterior multifocal placoid pigment epitheliopathy (APMPPE) is a rare inflammatory eye disease, affecting the inner choroid and the outer retina. Recent advances in multimodal imaging have been important in the understanding of the pathophysiology of the disease, allowing a better characterization of the morphology of this condition. Methods Narrative review. Results In this review, a comprehensive overview of clinical features, imaging findings, treatment management, and long-term outcomes of patients with APMPPE will be provided. Conclusions Although APMPPE was originally believed to be a self-limited condition with a good prognosis, the disease can be recurrent and result in significant loss of vision function. Fundus imaging plays an important role in the diagnosis and management of the disease, allowing to evaluate response to treatment and onset of complications.https://doi.org/10.1186/s12348-021-00263-1Acute posterior multifocal placoid pigment epitheliopathyAPMPPEPlacoid epiteliopathyImagingOptical coherence tomography angiography
spellingShingle Ilaria Testi
Sandra Vermeirsch
Carlos Pavesio
Acute posterior multifocal placoid pigment epitheliopathy (APMPPE)
Journal of Ophthalmic Inflammation and Infection
Acute posterior multifocal placoid pigment epitheliopathy
APMPPE
Placoid epiteliopathy
Imaging
Optical coherence tomography angiography
title Acute posterior multifocal placoid pigment epitheliopathy (APMPPE)
title_full Acute posterior multifocal placoid pigment epitheliopathy (APMPPE)
title_fullStr Acute posterior multifocal placoid pigment epitheliopathy (APMPPE)
title_full_unstemmed Acute posterior multifocal placoid pigment epitheliopathy (APMPPE)
title_short Acute posterior multifocal placoid pigment epitheliopathy (APMPPE)
title_sort acute posterior multifocal placoid pigment epitheliopathy apmppe
topic Acute posterior multifocal placoid pigment epitheliopathy
APMPPE
Placoid epiteliopathy
Imaging
Optical coherence tomography angiography
url https://doi.org/10.1186/s12348-021-00263-1
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