pH-Responsive Intra- and Inter-Molecularly Micelle Formation of Anionic Diblock Copolymer in Water
Poly(sodium2-(acrylamido)-2-methylpropanesulfonate)-block-poly(sodium11-(acrylamido)undecanoate) (PAMPS–PAaU) was synthesized via reversible addition-fragmentation chain transfer (RAFT)-controlled radical polymerization. The “living” polymerization of PAaU was evidenced by the fact that the molecula...
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| Format: | Article |
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MDPI AG
2016-02-01
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| Series: | Polymers |
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| Online Access: | http://www.mdpi.com/2073-4360/8/2/56 |
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| author | Masanobu Mizusaki Yoshihiko Shimada Yotaro Morishima Shin-ichi Yusa |
| author_facet | Masanobu Mizusaki Yoshihiko Shimada Yotaro Morishima Shin-ichi Yusa |
| author_sort | Masanobu Mizusaki |
| collection | DOAJ |
| description | Poly(sodium2-(acrylamido)-2-methylpropanesulfonate)-block-poly(sodium11-(acrylamido)undecanoate) (PAMPS–PAaU) was synthesized via reversible addition-fragmentation chain transfer (RAFT)-controlled radical polymerization. The “living” polymerization of PAaU was evidenced by the fact that the molecular weight distribution was narrow (Mw/Mn = 1.23). The pH-induced association behavior of PAMPS–PAaU in 0.1 M NaCl aqueous solutions as a function of solution pH was investigated by 1H NMR spin-spin relaxation time, dynamic light scattering (DLS), static light scattering (SLS), and fluorescence probe techniques. These results indicated that PAMPS–PAaU formed polymer micelles in 0.1 M NaCl aqueous solutions at pH < 9. At pH = 8–9, the polymer formed the micelles intramolecularly due to hydrophobic self-association of the PAaU block within the single polymer chain. On the other hand, at pH < 8, micellization occurred intermolecularly to form polymer micelles comprising hydrophobic PAaU cores and hydrophilic PAMPS shells. |
| first_indexed | 2024-04-13T19:43:26Z |
| format | Article |
| id | doaj.art-b4462399bdca42b58dcfa3f36f085f08 |
| institution | Directory Open Access Journal |
| issn | 2073-4360 |
| language | English |
| last_indexed | 2024-04-13T19:43:26Z |
| publishDate | 2016-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Polymers |
| spelling | doaj.art-b4462399bdca42b58dcfa3f36f085f082022-12-22T02:32:47ZengMDPI AGPolymers2073-43602016-02-01825610.3390/polym8020056polym8020056pH-Responsive Intra- and Inter-Molecularly Micelle Formation of Anionic Diblock Copolymer in WaterMasanobu Mizusaki0Yoshihiko Shimada1Yotaro Morishima2Shin-ichi Yusa3Department of Applied Chemistry, Graduate School of Engineering, University of Hyogo, 2167 Shosha, Himeji, Hyogo 671-2280, JapanDepartment of Applied Chemistry, Graduate School of Engineering, University of Hyogo, 2167 Shosha, Himeji, Hyogo 671-2280, JapanFaculty of Engineering, Fukui University of Technology, 6-3-1 Gakuen, Fukui 910-8505, JapanDepartment of Applied Chemistry, Graduate School of Engineering, University of Hyogo, 2167 Shosha, Himeji, Hyogo 671-2280, JapanPoly(sodium2-(acrylamido)-2-methylpropanesulfonate)-block-poly(sodium11-(acrylamido)undecanoate) (PAMPS–PAaU) was synthesized via reversible addition-fragmentation chain transfer (RAFT)-controlled radical polymerization. The “living” polymerization of PAaU was evidenced by the fact that the molecular weight distribution was narrow (Mw/Mn = 1.23). The pH-induced association behavior of PAMPS–PAaU in 0.1 M NaCl aqueous solutions as a function of solution pH was investigated by 1H NMR spin-spin relaxation time, dynamic light scattering (DLS), static light scattering (SLS), and fluorescence probe techniques. These results indicated that PAMPS–PAaU formed polymer micelles in 0.1 M NaCl aqueous solutions at pH < 9. At pH = 8–9, the polymer formed the micelles intramolecularly due to hydrophobic self-association of the PAaU block within the single polymer chain. On the other hand, at pH < 8, micellization occurred intermolecularly to form polymer micelles comprising hydrophobic PAaU cores and hydrophilic PAMPS shells.http://www.mdpi.com/2073-4360/8/2/56block copolymermicellesRAFT polymerizationwater-soluble polymerpH-responsive |
| spellingShingle | Masanobu Mizusaki Yoshihiko Shimada Yotaro Morishima Shin-ichi Yusa pH-Responsive Intra- and Inter-Molecularly Micelle Formation of Anionic Diblock Copolymer in Water Polymers block copolymer micelles RAFT polymerization water-soluble polymer pH-responsive |
| title | pH-Responsive Intra- and Inter-Molecularly Micelle Formation of Anionic Diblock Copolymer in Water |
| title_full | pH-Responsive Intra- and Inter-Molecularly Micelle Formation of Anionic Diblock Copolymer in Water |
| title_fullStr | pH-Responsive Intra- and Inter-Molecularly Micelle Formation of Anionic Diblock Copolymer in Water |
| title_full_unstemmed | pH-Responsive Intra- and Inter-Molecularly Micelle Formation of Anionic Diblock Copolymer in Water |
| title_short | pH-Responsive Intra- and Inter-Molecularly Micelle Formation of Anionic Diblock Copolymer in Water |
| title_sort | ph responsive intra and inter molecularly micelle formation of anionic diblock copolymer in water |
| topic | block copolymer micelles RAFT polymerization water-soluble polymer pH-responsive |
| url | http://www.mdpi.com/2073-4360/8/2/56 |
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