Substantial underestimation of SARS-CoV-2 infection in the United States

Estimating the extent of SARS-CoV-2 infection in a population is challenging due to the limitations of testing. Here, the authors estimate that the true number of infections in the United States in mid-April was up to 20 times higher than the number of confirmed cases.

Bibliographic Details
Main Authors: Sean L. Wu, Andrew N. Mertens, Yoshika S. Crider, Anna Nguyen, Nolan N. Pokpongkiat, Stephanie Djajadi, Anmol Seth, Michelle S. Hsiang, John M. Colford, Art Reingold, Benjamin F. Arnold, Alan Hubbard, Jade Benjamin-Chung
Format: Article
Language:English
Published: Nature Portfolio 2020-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-18272-4
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author Sean L. Wu
Andrew N. Mertens
Yoshika S. Crider
Anna Nguyen
Nolan N. Pokpongkiat
Stephanie Djajadi
Anmol Seth
Michelle S. Hsiang
John M. Colford
Art Reingold
Benjamin F. Arnold
Alan Hubbard
Jade Benjamin-Chung
author_facet Sean L. Wu
Andrew N. Mertens
Yoshika S. Crider
Anna Nguyen
Nolan N. Pokpongkiat
Stephanie Djajadi
Anmol Seth
Michelle S. Hsiang
John M. Colford
Art Reingold
Benjamin F. Arnold
Alan Hubbard
Jade Benjamin-Chung
author_sort Sean L. Wu
collection DOAJ
description Estimating the extent of SARS-CoV-2 infection in a population is challenging due to the limitations of testing. Here, the authors estimate that the true number of infections in the United States in mid-April was up to 20 times higher than the number of confirmed cases.
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spelling doaj.art-b446f7b11c1a46e3b5ae78349ccb4b332022-12-21T18:02:25ZengNature PortfolioNature Communications2041-17232020-09-0111111010.1038/s41467-020-18272-4Substantial underestimation of SARS-CoV-2 infection in the United StatesSean L. Wu0Andrew N. Mertens1Yoshika S. Crider2Anna Nguyen3Nolan N. Pokpongkiat4Stephanie Djajadi5Anmol Seth6Michelle S. Hsiang7John M. Colford8Art Reingold9Benjamin F. Arnold10Alan Hubbard11Jade Benjamin-Chung12Division of Epidemiology and Biostatistics, University of CaliforniaDivision of Epidemiology and Biostatistics, University of CaliforniaDivision of Epidemiology and Biostatistics, University of CaliforniaDivision of Epidemiology and Biostatistics, University of CaliforniaDivision of Epidemiology and Biostatistics, University of CaliforniaDivision of Epidemiology and Biostatistics, University of CaliforniaDivision of Epidemiology and Biostatistics, University of CaliforniaDepartment of Pediatrics, University of Texas Southwestern Medical CenterDivision of Epidemiology and Biostatistics, University of CaliforniaDivision of Epidemiology and Biostatistics, University of CaliforniaFrancis I. Proctor Foundation, University of CaliforniaDivision of Epidemiology and Biostatistics, University of CaliforniaDivision of Epidemiology and Biostatistics, University of CaliforniaEstimating the extent of SARS-CoV-2 infection in a population is challenging due to the limitations of testing. Here, the authors estimate that the true number of infections in the United States in mid-April was up to 20 times higher than the number of confirmed cases.https://doi.org/10.1038/s41467-020-18272-4
spellingShingle Sean L. Wu
Andrew N. Mertens
Yoshika S. Crider
Anna Nguyen
Nolan N. Pokpongkiat
Stephanie Djajadi
Anmol Seth
Michelle S. Hsiang
John M. Colford
Art Reingold
Benjamin F. Arnold
Alan Hubbard
Jade Benjamin-Chung
Substantial underestimation of SARS-CoV-2 infection in the United States
Nature Communications
title Substantial underestimation of SARS-CoV-2 infection in the United States
title_full Substantial underestimation of SARS-CoV-2 infection in the United States
title_fullStr Substantial underestimation of SARS-CoV-2 infection in the United States
title_full_unstemmed Substantial underestimation of SARS-CoV-2 infection in the United States
title_short Substantial underestimation of SARS-CoV-2 infection in the United States
title_sort substantial underestimation of sars cov 2 infection in the united states
url https://doi.org/10.1038/s41467-020-18272-4
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