Identification of CNS Injury-Related microRNAs as Novel Toll-Like Receptor 7/8 Signaling Activators by Small RNA Sequencing

Identification of CNS Injury-Related microRNAs as Novel Toll-Like Receptor 7/8 Signaling Activators by Small RNA Sequencing

Toll-like receptors (TLRs) belong to pattern recognition receptors, which respond to danger signals such as pathogen-associated molecular patterns or damage-associated molecular patterns. Upon TLR activation in microglia, the major immune cells in the brain, distinct signaling cascades trigger the p...

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Bibliographic Details
Main Authors: Thomas Wallach, Max Wetzel, Paul Dembny, Ori Staszewski, Christina Krüger, Alice Buonfiglioli, Marco Prinz, Seija Lehnardt
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:Cells
Subjects:
microrna
toll-like receptor
microglia
neurons
neurodegeneration
small rna sequencing
Online Access:https://www.mdpi.com/2073-4409/9/1/186

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