Multi-detector CT chest: can it omit the further need for contrast enhnaced spectral mammography in breast cancer patients candidate for CT staging?
Abstract Background During multi-detector computed tomography (MDCT) of the chest, incidental breast lesions (IBLs) are occasionally encountered. Mammography remains the gold standard for the early detection of breast cancer. However, limitations exist in patients with dense breasts. Contrast spectr...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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SpringerOpen
2022-07-01
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| Series: | The Egyptian Journal of Radiology and Nuclear Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s43055-022-00826-9 |
| _version_ | 1817968760334581760 |
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| author | Rasha Wessam Abdel Rahman Salwa Yahya Ahmed Al-Dhurani Amira Hamed Radwan Ahmed Abdellatif Mohamed Eman Faker Kamal |
| author_facet | Rasha Wessam Abdel Rahman Salwa Yahya Ahmed Al-Dhurani Amira Hamed Radwan Ahmed Abdellatif Mohamed Eman Faker Kamal |
| author_sort | Rasha Wessam Abdel Rahman |
| collection | DOAJ |
| description | Abstract Background During multi-detector computed tomography (MDCT) of the chest, incidental breast lesions (IBLs) are occasionally encountered. Mammography remains the gold standard for the early detection of breast cancer. However, limitations exist in patients with dense breasts. Contrast spectral mammography (CESM) is widely available compared to MRI; it increases the sensitivity for breast cancer detection without decreasing the specificity. Results The study is a prospective study that included 113 female breast cancer patients for CT staging. One hundred and six of the patients had unilateral carcinoma and 7 of them had bilateral cancer with a total of 120 breasts evaluated. The CT findings were correlated with CESM findings regarding the multiplicity and bilaterality of the disease. The sensitivity, specificity, PPV, NPV, and accuracy of the CT in the detection of multiplicity were 97.44%, 100%, 100%, 95.45%, and 98.33%, respectively, and the sensitivity, specificity, PPV, NPV, and accuracy of the CT in the detection of bilateral disease were 68.18%, 97.96%, 88.24%, 93.20%, and 92.50%, respectively. Conclusions Breast cancer patients for MDCT chest as a part of their metastatic workup can omit the further need for CESM. |
| first_indexed | 2024-04-13T20:12:06Z |
| format | Article |
| id | doaj.art-b44a596a7a124dee8dd346b0b45dad3a |
| institution | Directory Open Access Journal |
| issn | 2090-4762 |
| language | English |
| last_indexed | 2024-04-13T20:12:06Z |
| publishDate | 2022-07-01 |
| publisher | SpringerOpen |
| record_format | Article |
| series | The Egyptian Journal of Radiology and Nuclear Medicine |
| spelling | doaj.art-b44a596a7a124dee8dd346b0b45dad3a2022-12-22T02:31:48ZengSpringerOpenThe Egyptian Journal of Radiology and Nuclear Medicine2090-47622022-07-015311810.1186/s43055-022-00826-9Multi-detector CT chest: can it omit the further need for contrast enhnaced spectral mammography in breast cancer patients candidate for CT staging?Rasha Wessam Abdel Rahman0Salwa Yahya Ahmed Al-Dhurani1Amira Hamed Radwan2Ahmed Abdellatif Mohamed3Eman Faker Kamal4Radiology Department, Cairo UniversityRadiology Department, Cairo UniversityBaheya Center for Early Detection and Treatment of Breast CancerBaheya Center for Early Detection and Treatment of Breast CancerRadiology Department, Cairo UniversityAbstract Background During multi-detector computed tomography (MDCT) of the chest, incidental breast lesions (IBLs) are occasionally encountered. Mammography remains the gold standard for the early detection of breast cancer. However, limitations exist in patients with dense breasts. Contrast spectral mammography (CESM) is widely available compared to MRI; it increases the sensitivity for breast cancer detection without decreasing the specificity. Results The study is a prospective study that included 113 female breast cancer patients for CT staging. One hundred and six of the patients had unilateral carcinoma and 7 of them had bilateral cancer with a total of 120 breasts evaluated. The CT findings were correlated with CESM findings regarding the multiplicity and bilaterality of the disease. The sensitivity, specificity, PPV, NPV, and accuracy of the CT in the detection of multiplicity were 97.44%, 100%, 100%, 95.45%, and 98.33%, respectively, and the sensitivity, specificity, PPV, NPV, and accuracy of the CT in the detection of bilateral disease were 68.18%, 97.96%, 88.24%, 93.20%, and 92.50%, respectively. Conclusions Breast cancer patients for MDCT chest as a part of their metastatic workup can omit the further need for CESM.https://doi.org/10.1186/s43055-022-00826-9Contrast-enhanced spectral mammographyMulti-detector CTMultifocalMulticentric |
| spellingShingle | Rasha Wessam Abdel Rahman Salwa Yahya Ahmed Al-Dhurani Amira Hamed Radwan Ahmed Abdellatif Mohamed Eman Faker Kamal Multi-detector CT chest: can it omit the further need for contrast enhnaced spectral mammography in breast cancer patients candidate for CT staging? The Egyptian Journal of Radiology and Nuclear Medicine Contrast-enhanced spectral mammography Multi-detector CT Multifocal Multicentric |
| title | Multi-detector CT chest: can it omit the further need for contrast enhnaced spectral mammography in breast cancer patients candidate for CT staging? |
| title_full | Multi-detector CT chest: can it omit the further need for contrast enhnaced spectral mammography in breast cancer patients candidate for CT staging? |
| title_fullStr | Multi-detector CT chest: can it omit the further need for contrast enhnaced spectral mammography in breast cancer patients candidate for CT staging? |
| title_full_unstemmed | Multi-detector CT chest: can it omit the further need for contrast enhnaced spectral mammography in breast cancer patients candidate for CT staging? |
| title_short | Multi-detector CT chest: can it omit the further need for contrast enhnaced spectral mammography in breast cancer patients candidate for CT staging? |
| title_sort | multi detector ct chest can it omit the further need for contrast enhnaced spectral mammography in breast cancer patients candidate for ct staging |
| topic | Contrast-enhanced spectral mammography Multi-detector CT Multifocal Multicentric |
| url | https://doi.org/10.1186/s43055-022-00826-9 |
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