Molecular pathogenesis of sporadic colorectal cancers

Molecular pathogenesis of sporadic colorectal cancers

Abstract Colorectal cancer (CRC) results from the progressive accumulation of genetic and epigenetic alterations that lead to the transformation of normal colonic mucosa to adenocarcinoma. Approximately 75% of CRCs are sporadic and occur in people without genetic predisposition or family history of...

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Bibliographic Details
Main Authors: Hidetsugu Yamagishi, Hajime Kuroda, Yasuo Imai, Hideyuki Hiraishi
Format: Article
Language:English
Published: BMC 2016-01-01
Series:Chinese Journal of Cancer
Subjects:
Sporadic colorectal cancer
Pathogenesis
Morphology
Large-scale genome analysis
Genetic pathway
Online Access:http://link.springer.com/article/10.1186/s40880-015-0066-y

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