Endoscopic calcium electroporation for colorectal cancer: a phase I study

Background and study aims Colorectal cancer is one of the most common malignancies, with approximately 20 % of patients having metastatic disease. Local symptoms from the tumor remain a common issue and affect quality of life. Electroporation is a method to permeabilize cell membranes wit...

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Bibliographic Details
Main Authors: Broholm Broholm, Vogelsang Vogelsang, Bulut Bulut, Stigaard Stigaard, Falk Falk, Frandsen Frandsen, Pedersen Pedersen, Perner Perner, Fiehn Fiehn, Mølholm Mølholm, Bzorek Bzorek, Rosen Rosen, Andersen Andersen, Pallisgaard Pallisgaard, Gögenur Gögenur, Gehl Gehl
Format: Article
Language:English
Published: Georg Thieme Verlag KG 2023-05-01
Series:Endoscopy International Open
Online Access:http://www.thieme-connect.de/DOI/DOI?10.1055/a-2033-9831
Description
Summary:Background and study aims Colorectal cancer is one of the most common malignancies, with approximately 20 % of patients having metastatic disease. Local symptoms from the tumor remain a common issue and affect quality of life. Electroporation is a method to permeabilize cell membranes with high-voltage pulses, allowing increased passage of otherwise poorly permeating substances such as calcium. The aim of this study was to determine the safety of calcium electroporation for advanced colorectal cancer.
ISSN:2364-3722
2196-9736