Lyophilized Iron Oxide Nanoparticles Encapsulated in Amphotericin B: A Novel Targeted Nano Drug Delivery System for the Treatment of Systemic Fungal Infections

Lyophilized Iron Oxide Nanoparticles Encapsulated in Amphotericin B: A Novel Targeted Nano Drug Delivery System for the Treatment of Systemic Fungal Infections

We formulated and tested a targeted nanodrug delivery system to help treat life-threatening invasive fungal infections, such as cryptococcal meningitis. Various designs of iron oxide nanoparticles (IONP) (34−40 nm) coated with bovine serum albumin and coated and targeted with amphotericin...

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Bibliographic Details
Main Authors: Pavan Balabathula, Sarah Garland Whaley, Dileep R. Janagam, Nivesh K. Mittal, Bivash Mandal, Laura A. Thoma, P. David Rogers, George C. Wood
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Pharmaceutics
Subjects:
nanoparticle(s)
theranostics
targeted drug delivery
antiinfective(s)
lyophilization
albumin
drug delivery system(s)
drug transport
colloid(s)
coating
Online Access:https://www.mdpi.com/1999-4923/12/3/247

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