Is either arterial or venous antithrombin III level linked to outcome in elderly males versus females with severe sepsis?
Objectives: We aimed to study arterial and venous ATIII levels, in elderly males and females with severe sepsis, and their impact upon the patients’ outcomes. Patients and Methods: A cohort study was performed in thirty-nine elderly patients with severe sepsis. Arterial and venous ATIII levels we...
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| Format: | Article |
| Language: | English |
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Manipal College of Medical Sciences, Pokhara
2014-07-01
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| Series: | Asian Journal of Medical Sciences |
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| Online Access: | https://www.nepjol.info/index.php/AJMS/article/view/10795 |
| _version_ | 1818455717049270272 |
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| author | Nermien N Adly |
| author_facet | Nermien N Adly |
| author_sort | Nermien N Adly |
| collection | DOAJ |
| description | Objectives: We aimed to study arterial and venous ATIII levels, in elderly males and females with severe sepsis, and their impact upon the patients’ outcomes.
Patients and Methods: A cohort study was performed in thirty-nine elderly patients with severe sepsis. Arterial and venous ATIII levels were measured. Sequential Organ Failure Assessment (SOFA) score was calculated.
Results: Both arterial and venous ATIII levels were negatively correlated with age in the whole sample (P=0.004 and .05 consecutively) (r = −0.45 and −0.32 consecutively). There was a significant difference between the arterial and venous ATIII levels in males (P=0.04). In males, SOFA score was positively correlated with arterial ATIII and the difference between arterial and venous ATIII levels (P=0.04 and .05 consecutively). Arterial and venous ATIII were the significant predictors of SOFA score, only in males (P <0.001 and 0.003 consecutively).
Conclusion: ATIII level decreased with increasing age. In males, both higher arterial and lower venous ATIII levels were significant predictors of worse organ dysfunction. |
| first_indexed | 2024-12-14T22:15:12Z |
| format | Article |
| id | doaj.art-b44f3f56fe05490dbb15a2d9789dde5a |
| institution | Directory Open Access Journal |
| issn | 2467-9100 2091-0576 |
| language | English |
| last_indexed | 2024-12-14T22:15:12Z |
| publishDate | 2014-07-01 |
| publisher | Manipal College of Medical Sciences, Pokhara |
| record_format | Article |
| series | Asian Journal of Medical Sciences |
| spelling | doaj.art-b44f3f56fe05490dbb15a2d9789dde5a2022-12-21T22:45:38ZengManipal College of Medical Sciences, PokharaAsian Journal of Medical Sciences2467-91002091-05762014-07-01613439https://doi.org/10.3126/ajms.v6i1.10795Is either arterial or venous antithrombin III level linked to outcome in elderly males versus females with severe sepsis?Nermien N Adly 0Lecturer of Geriatric Medicine, Geriatrics and Gerontology Department, Faculty of Medicine, Ain Shams University, CairoObjectives: We aimed to study arterial and venous ATIII levels, in elderly males and females with severe sepsis, and their impact upon the patients’ outcomes. Patients and Methods: A cohort study was performed in thirty-nine elderly patients with severe sepsis. Arterial and venous ATIII levels were measured. Sequential Organ Failure Assessment (SOFA) score was calculated. Results: Both arterial and venous ATIII levels were negatively correlated with age in the whole sample (P=0.004 and .05 consecutively) (r = −0.45 and −0.32 consecutively). There was a significant difference between the arterial and venous ATIII levels in males (P=0.04). In males, SOFA score was positively correlated with arterial ATIII and the difference between arterial and venous ATIII levels (P=0.04 and .05 consecutively). Arterial and venous ATIII were the significant predictors of SOFA score, only in males (P <0.001 and 0.003 consecutively). Conclusion: ATIII level decreased with increasing age. In males, both higher arterial and lower venous ATIII levels were significant predictors of worse organ dysfunction.https://www.nepjol.info/index.php/AJMS/article/view/10795severe sepsisgenderantithrombin iiioutcomesofaelderlyegypt |
| spellingShingle | Nermien N Adly Is either arterial or venous antithrombin III level linked to outcome in elderly males versus females with severe sepsis? Asian Journal of Medical Sciences severe sepsis gender antithrombin iii outcome sofa elderly egypt |
| title | Is either arterial or venous antithrombin III level linked to outcome in elderly males versus females with severe sepsis? |
| title_full | Is either arterial or venous antithrombin III level linked to outcome in elderly males versus females with severe sepsis? |
| title_fullStr | Is either arterial or venous antithrombin III level linked to outcome in elderly males versus females with severe sepsis? |
| title_full_unstemmed | Is either arterial or venous antithrombin III level linked to outcome in elderly males versus females with severe sepsis? |
| title_short | Is either arterial or venous antithrombin III level linked to outcome in elderly males versus females with severe sepsis? |
| title_sort | is either arterial or venous antithrombin iii level linked to outcome in elderly males versus females with severe sepsis |
| topic | severe sepsis gender antithrombin iii outcome sofa elderly egypt |
| url | https://www.nepjol.info/index.php/AJMS/article/view/10795 |
| work_keys_str_mv | AT nermiennadly iseitherarterialorvenousantithrombiniiilevellinkedtooutcomeinelderlymalesversusfemaleswithseveresepsis |