Ischemia Reperfusion Injury Triggers CXCL13 Release and B-Cell Recruitment After Allogenic Kidney Transplantation

Ischemia Reperfusion Injury Triggers CXCL13 Release and B-Cell Recruitment After Allogenic Kidney Transplantation

Ischemia reperfusion injury (IRI) is linked with inflammation in kidney transplantation (ktx). The chemokine CXCL13, also known as B lymphocyte chemoattractant, mediates recruitment of B cells within follicles of lymphoid tissues and has recently been identified as a biomarker for acute kidney allog...

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Bibliographic Details
Main Authors: Kirill Kreimann, Mi-Sun Jang, Song Rong, Robert Greite, Sibylle von Vietinghoff, Roland Schmitt, Jan Hinrich Bräsen, Lena Schiffer, Jessica Gerstenberg, Vijith Vijayan, Oliver Dittrich-Breiholz, Li Wang, Christian M. Karsten, Wilfried Gwinner, Hermann Haller, Stephan Immenschuh, Faikah Gueler
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Immunology
Subjects:
ischemia reperfusion injury
delayed graft function
kidney transplantation
B-cell activation
CXCL13
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.01204/full

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