Spermatogenesis in Mice exposed to Hydroxyurea: Protecitve effect of ntural apple cider vinegar

The effect of hydroxyurea at a close of 80mg/kg/day orally for (7) days on Spermatogenesis and the protective role of NACV (Natural apple cider vinegar) has been studied in mature male mice. Hydroxyurea caused a reduction in the number of spermatogonia and a significant decrease in primary spermatoc...

Full description

Bibliographic Details
Main Authors: Aticka El-Nouri, Rafah Ayoub
Format: Article
Language:Arabic
Published: College of Education for Pure Sciences 2005-06-01
Series:مجلة التربية والعلم
Subjects:
Online Access:https://edusj.mosuljournals.com/article_82503_309240184162d9f51cda3a4b50a2e947.pdf
_version_ 1819033445069750272
author Aticka El-Nouri
Rafah Ayoub
author_facet Aticka El-Nouri
Rafah Ayoub
author_sort Aticka El-Nouri
collection DOAJ
description The effect of hydroxyurea at a close of 80mg/kg/day orally for (7) days on Spermatogenesis and the protective role of NACV (Natural apple cider vinegar) has been studied in mature male mice. Hydroxyurea caused a reduction in the number of spermatogonia and a significant decrease in primary spermatocytes and spermatids. Administration .of natural apple cider vinegar (20mg/kg/day) for (7) days after hydroxyurea caused a significant decrease in spermatogonia, spermatocytes and spermatids. The administration of natural apple cider vinegar with hydroxyurea produced a significant increase in the diameter of seminiferous tubules and spermatocyte count and an increase in spermatogonia count, while spermatid count did not return to normal. The present data indicate that hydroxyurea exerts inhibitory action on spermatogenesis, and natural apple cider vinegar has a protective effect against the damaging effect of hydroxyurea .
first_indexed 2024-12-21T07:17:57Z
format Article
id doaj.art-b4566b70357d4ab0bab04bdd7767a5cc
institution Directory Open Access Journal
issn 1812-125X
2664-2530
language Arabic
last_indexed 2024-12-21T07:17:57Z
publishDate 2005-06-01
publisher College of Education for Pure Sciences
record_format Article
series مجلة التربية والعلم
spelling doaj.art-b4566b70357d4ab0bab04bdd7767a5cc2022-12-21T19:11:50ZaraCollege of Education for Pure Sciencesمجلة التربية والعلم1812-125X2664-25302005-06-01173687210.33899/edusj.2005.8250382503Spermatogenesis in Mice exposed to Hydroxyurea: Protecitve effect of ntural apple cider vinegarAticka El-NouriRafah AyoubThe effect of hydroxyurea at a close of 80mg/kg/day orally for (7) days on Spermatogenesis and the protective role of NACV (Natural apple cider vinegar) has been studied in mature male mice. Hydroxyurea caused a reduction in the number of spermatogonia and a significant decrease in primary spermatocytes and spermatids. Administration .of natural apple cider vinegar (20mg/kg/day) for (7) days after hydroxyurea caused a significant decrease in spermatogonia, spermatocytes and spermatids. The administration of natural apple cider vinegar with hydroxyurea produced a significant increase in the diameter of seminiferous tubules and spermatocyte count and an increase in spermatogonia count, while spermatid count did not return to normal. The present data indicate that hydroxyurea exerts inhibitory action on spermatogenesis, and natural apple cider vinegar has a protective effect against the damaging effect of hydroxyurea .https://edusj.mosuljournals.com/article_82503_309240184162d9f51cda3a4b50a2e947.pdfmice exposedhydroxyureaapple cider vinegar
spellingShingle Aticka El-Nouri
Rafah Ayoub
Spermatogenesis in Mice exposed to Hydroxyurea: Protecitve effect of ntural apple cider vinegar
مجلة التربية والعلم
mice exposed
hydroxyurea
apple cider vinegar
title Spermatogenesis in Mice exposed to Hydroxyurea: Protecitve effect of ntural apple cider vinegar
title_full Spermatogenesis in Mice exposed to Hydroxyurea: Protecitve effect of ntural apple cider vinegar
title_fullStr Spermatogenesis in Mice exposed to Hydroxyurea: Protecitve effect of ntural apple cider vinegar
title_full_unstemmed Spermatogenesis in Mice exposed to Hydroxyurea: Protecitve effect of ntural apple cider vinegar
title_short Spermatogenesis in Mice exposed to Hydroxyurea: Protecitve effect of ntural apple cider vinegar
title_sort spermatogenesis in mice exposed to hydroxyurea protecitve effect of ntural apple cider vinegar
topic mice exposed
hydroxyurea
apple cider vinegar
url https://edusj.mosuljournals.com/article_82503_309240184162d9f51cda3a4b50a2e947.pdf
work_keys_str_mv AT atickaelnouri spermatogenesisinmiceexposedtohydroxyureaprotecitveeffectofnturalapplecidervinegar
AT rafahayoub spermatogenesisinmiceexposedtohydroxyureaprotecitveeffectofnturalapplecidervinegar