Thyroid-stimulating hormone-secreting pituitary adenoma presenting with recurrent hyperthyroidism in post-treated Graves’ disease: a case report
<p>Abstract</p> <p>Introduction</p> <p>The coexistence of autoimmune hyperthyroid disease and thyroid-stimulating hormone-secreting pituitary adenoma is rare. The simple presumption of coincidence of these two diseases has a calculated incidence of less than one/several...
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| Format: | Article |
| Language: | English |
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BMC
2013-01-01
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| Series: | Journal of Medical Case Reports |
| Subjects: | |
| Online Access: | http://www.jmedicalcasereports.com/content/7/1/27 |
| _version_ | 1819140744548450304 |
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| author | Ogawa Yoshikazu Tominaga Teiji |
| author_facet | Ogawa Yoshikazu Tominaga Teiji |
| author_sort | Ogawa Yoshikazu |
| collection | DOAJ |
| description | <p>Abstract</p> <p>Introduction</p> <p>The coexistence of autoimmune hyperthyroid disease and thyroid-stimulating hormone-secreting pituitary adenoma is rare. The simple presumption of coincidence of these two diseases has a calculated incidence of less than one/several hundred million, and only four cases with histological confirmation have been reported. A rapid decrease in thyroid-stimulating hormone level after pituitary tumor removal may induce subsequent activation of autoimmune responses against the thyroid gland. We report the first case of a sequential and paradoxical occurrence of Graves’ disease and a thyroid-stimulating hormone-secreting pituitary adenoma.</p> <p>Case presentation</p> <p>A 32-year-old Japanese woman had recurrent hyperthyroidism. She had a history of Graves’ hyperthyroidism, which had been successfully treated with propylthiouracil. A head magnetic resonance imaging showed a less enhanced area in the left lateral wing of her sella turcica. Transsphenoidal surgery was performed, and the diagnosis was established as thyroid-stimulating hormone-secreting plurihormonal adenoma. A rapid reduction in thyroid hormone levels was achieved, and her blood pressure was normalized after the operation.</p> <p>Conclusion</p> <p>Although incidental occurrence is the most probable etiology, long and repeated followup examinations of both thyroid and pituitary gland should be performed in patients with an atypical clinical course.</p> |
| first_indexed | 2024-12-22T11:43:25Z |
| format | Article |
| id | doaj.art-b45bad0ca0f24e61a0a219dbaea6708e |
| institution | Directory Open Access Journal |
| issn | 1752-1947 |
| language | English |
| last_indexed | 2024-12-22T11:43:25Z |
| publishDate | 2013-01-01 |
| publisher | BMC |
| record_format | Article |
| series | Journal of Medical Case Reports |
| spelling | doaj.art-b45bad0ca0f24e61a0a219dbaea6708e2022-12-21T18:27:13ZengBMCJournal of Medical Case Reports1752-19472013-01-01712710.1186/1752-1947-7-27Thyroid-stimulating hormone-secreting pituitary adenoma presenting with recurrent hyperthyroidism in post-treated Graves’ disease: a case reportOgawa YoshikazuTominaga Teiji<p>Abstract</p> <p>Introduction</p> <p>The coexistence of autoimmune hyperthyroid disease and thyroid-stimulating hormone-secreting pituitary adenoma is rare. The simple presumption of coincidence of these two diseases has a calculated incidence of less than one/several hundred million, and only four cases with histological confirmation have been reported. A rapid decrease in thyroid-stimulating hormone level after pituitary tumor removal may induce subsequent activation of autoimmune responses against the thyroid gland. We report the first case of a sequential and paradoxical occurrence of Graves’ disease and a thyroid-stimulating hormone-secreting pituitary adenoma.</p> <p>Case presentation</p> <p>A 32-year-old Japanese woman had recurrent hyperthyroidism. She had a history of Graves’ hyperthyroidism, which had been successfully treated with propylthiouracil. A head magnetic resonance imaging showed a less enhanced area in the left lateral wing of her sella turcica. Transsphenoidal surgery was performed, and the diagnosis was established as thyroid-stimulating hormone-secreting plurihormonal adenoma. A rapid reduction in thyroid hormone levels was achieved, and her blood pressure was normalized after the operation.</p> <p>Conclusion</p> <p>Although incidental occurrence is the most probable etiology, long and repeated followup examinations of both thyroid and pituitary gland should be performed in patients with an atypical clinical course.</p>http://www.jmedicalcasereports.com/content/7/1/27Graves’ diseasePituitary adenomaSequential occurrenceTSH |
| spellingShingle | Ogawa Yoshikazu Tominaga Teiji Thyroid-stimulating hormone-secreting pituitary adenoma presenting with recurrent hyperthyroidism in post-treated Graves’ disease: a case report Journal of Medical Case Reports Graves’ disease Pituitary adenoma Sequential occurrence TSH |
| title | Thyroid-stimulating hormone-secreting pituitary adenoma presenting with recurrent hyperthyroidism in post-treated Graves’ disease: a case report |
| title_full | Thyroid-stimulating hormone-secreting pituitary adenoma presenting with recurrent hyperthyroidism in post-treated Graves’ disease: a case report |
| title_fullStr | Thyroid-stimulating hormone-secreting pituitary adenoma presenting with recurrent hyperthyroidism in post-treated Graves’ disease: a case report |
| title_full_unstemmed | Thyroid-stimulating hormone-secreting pituitary adenoma presenting with recurrent hyperthyroidism in post-treated Graves’ disease: a case report |
| title_short | Thyroid-stimulating hormone-secreting pituitary adenoma presenting with recurrent hyperthyroidism in post-treated Graves’ disease: a case report |
| title_sort | thyroid stimulating hormone secreting pituitary adenoma presenting with recurrent hyperthyroidism in post treated graves disease a case report |
| topic | Graves’ disease Pituitary adenoma Sequential occurrence TSH |
| url | http://www.jmedicalcasereports.com/content/7/1/27 |
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