Advantages of Cubosomal Formulation for Gatifloxacin Delivery in the Treatment of Bacterial Keratitis: In Vitro and In Vivo Approach Using Clinical Isolate of Methicillin-Resistant <i>Staphylococcus aureus</i>

Advantages of Cubosomal Formulation for Gatifloxacin Delivery in the Treatment of Bacterial Keratitis: In Vitro and In Vivo Approach Using Clinical Isolate of Methicillin-Resistant <i>Staphylococcus aureus</i>

The objective of this study was to enhance the corneal permeation of gatifloxacin (GTX) using cubosomal nanoparticle as a delivery system. Cubosomal nanoparticle loaded with GTX was prepared and subjected for in vitro and in vivo investigations. The prepared GTX-loaded cubosomal particles exhibited...

Full description

Bibliographic Details
Main Authors: Mohamed Nasr, Sameh Saber, Alaa Y. Bazeed, Heba A. Ramadan, Asmaa Ebada, Adela Laura Ciorba, Simona Cavalu, Heba I. Elagamy
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Materials
Subjects:
gatifloxacin
cubosomal dispersion
MIC
corneal permeation
methicillin resistant <i>Staphylococcus aureus</i>
keratitis
Online Access:https://www.mdpi.com/1996-1944/15/9/3374

Internet

https://www.mdpi.com/1996-1944/15/9/3374

Similar Items