Screening Procedure for Hemihypertrophy: Preliminary Results of International Multicenter Prospective Study
Introduction: Isolated or congenital hemihypertrophy is a rare disorder characterized by asymmetric overgrowth of one side of the body. This article describes the protocol and preliminary results of a lateral body asymmetry (hemihypertrophy) screening procedure performed in healthy adolescents in a...
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| Format: | Article |
| Language: | English |
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University Library System, University of Pittsburgh
2019-03-01
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| Series: | Central Asian Journal of Global Health |
| Subjects: | |
| Online Access: | http://cajgh.pitt.edu/ojs/index.php/cajgh/article/view/336 |
| _version_ | 1818651789172408320 |
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| author | Michael Vaiman Phillip Shilco Yulia Roitblat Nicolas Padilla-Raygoza Aidan Leit Aaron Kavin Edan Schonberger Liliia Nehuliaieva Noa Buchris Michael Shterenshis |
| author_facet | Michael Vaiman Phillip Shilco Yulia Roitblat Nicolas Padilla-Raygoza Aidan Leit Aaron Kavin Edan Schonberger Liliia Nehuliaieva Noa Buchris Michael Shterenshis |
| author_sort | Michael Vaiman |
| collection | DOAJ |
| description | Introduction: Isolated or congenital hemihypertrophy is a rare disorder characterized by asymmetric overgrowth of one side of the body. This article describes the protocol and preliminary results of a lateral body asymmetry (hemihypertrophy) screening procedure performed in healthy adolescents in a multicenter study. The reported incidence of hemihypertrophy varies between different publications and standardized protocols are needed to improve research in this area.
Methods: Our screening program is taking place in Australia, Israel, Mexico, Ukraine and USA. Procedure includes two steps: (1) “three measurements – three questions” screening, or assessment of face, palms, and shins; (2) in-depth assessment of selected cases in order to exclude localized, lesional, and syndrome-related cases as well as body asymmetry within normative range and to select suspected cases of isolated hemihypertrophy. This step includes measurements of various anatomical regions and a detailed questionnaire.
Results: At this stage, the screening procedure is completed and the selected participants are advised to refer to medical institutions for further clinical and genetic follow up to exclude possible tumors and other accompanying disorders.
Conclusion: We present an easy-to-use selection tool to identify children with suspected IH, which results in the selection of the risk group that may benefit from referral to a pediatrician and a clinical geneticist. |
| first_indexed | 2024-12-17T02:11:41Z |
| format | Article |
| id | doaj.art-b46562be0ccf45a9b214400f0fc24091 |
| institution | Directory Open Access Journal |
| issn | 2166-7403 |
| language | English |
| last_indexed | 2024-12-17T02:11:41Z |
| publishDate | 2019-03-01 |
| publisher | University Library System, University of Pittsburgh |
| record_format | Article |
| series | Central Asian Journal of Global Health |
| spelling | doaj.art-b46562be0ccf45a9b214400f0fc240912022-12-21T22:07:31ZengUniversity Library System, University of PittsburghCentral Asian Journal of Global Health2166-74032019-03-018110.5195/cajgh.2019.336163Screening Procedure for Hemihypertrophy: Preliminary Results of International Multicenter Prospective StudyMichael Vaiman0Phillip Shilco1Yulia Roitblat2Nicolas Padilla-Raygoza3Aidan Leit4Aaron Kavin5Edan Schonberger6Liliia Nehuliaieva7Noa Buchris8Michael Shterenshis9Department of Otolaryngology, Assaf Harofeh Medical Center, Affiliated with Sackler Faculty of Medicine, Tel Aviv University, Tel-Aviv, Israel“Briut HaShen” Dental Health Clinic, Jerusalem, Israel Science Research Department, Alexander Muss High School in Israel (AMHSI) affiliated with Alexander Muss Institute for Israel Education (AMIIE), Hod HaSharon, IsraelDepartment of Sciences, Belkind School for Special Education, Rishon-LeZion, IsraelDepartment of Nursing and Obstetrics, Division of Health Sciences and Engineering, Campus Celaya-Salvatierra, University of Guanajuato, MexicoDepartment of Sciences, The Harley School, Rochester, NY, USADepartment of Anatomy, Mount Moriah College, Sydney, AustraliaDepartment of Anatomy, Mount Moriah College, Sydney, AustraliaDepartment of Pediatrics, Danylo Halytsky Lviv National Medical University, Lviv, UkraineDept. of Sciences, El Camino Real Charter High School, Woodland Hills, CA, USA Science Research Department, Alexander Muss High School in Israel (AMHSI) affiliated with Alexander Muss Institute for Israel Education (AMIIE), Hod HaSharon, IsraelScience Research Department, Alexander Muss High School in Israel (AMHSI) affiliated with Alexander Muss Institute for Israel Education (AMIIE), Hod HaSharon, IsraelIntroduction: Isolated or congenital hemihypertrophy is a rare disorder characterized by asymmetric overgrowth of one side of the body. This article describes the protocol and preliminary results of a lateral body asymmetry (hemihypertrophy) screening procedure performed in healthy adolescents in a multicenter study. The reported incidence of hemihypertrophy varies between different publications and standardized protocols are needed to improve research in this area. Methods: Our screening program is taking place in Australia, Israel, Mexico, Ukraine and USA. Procedure includes two steps: (1) “three measurements – three questions” screening, or assessment of face, palms, and shins; (2) in-depth assessment of selected cases in order to exclude localized, lesional, and syndrome-related cases as well as body asymmetry within normative range and to select suspected cases of isolated hemihypertrophy. This step includes measurements of various anatomical regions and a detailed questionnaire. Results: At this stage, the screening procedure is completed and the selected participants are advised to refer to medical institutions for further clinical and genetic follow up to exclude possible tumors and other accompanying disorders. Conclusion: We present an easy-to-use selection tool to identify children with suspected IH, which results in the selection of the risk group that may benefit from referral to a pediatrician and a clinical geneticist.http://cajgh.pitt.edu/ojs/index.php/cajgh/article/view/336HemihypertrophyHemihyperplasiaAsymmetric regional body overgrowthBody asymmetryAdolescents |
| spellingShingle | Michael Vaiman Phillip Shilco Yulia Roitblat Nicolas Padilla-Raygoza Aidan Leit Aaron Kavin Edan Schonberger Liliia Nehuliaieva Noa Buchris Michael Shterenshis Screening Procedure for Hemihypertrophy: Preliminary Results of International Multicenter Prospective Study Central Asian Journal of Global Health Hemihypertrophy Hemihyperplasia Asymmetric regional body overgrowth Body asymmetry Adolescents |
| title | Screening Procedure for Hemihypertrophy: Preliminary Results of International Multicenter Prospective Study |
| title_full | Screening Procedure for Hemihypertrophy: Preliminary Results of International Multicenter Prospective Study |
| title_fullStr | Screening Procedure for Hemihypertrophy: Preliminary Results of International Multicenter Prospective Study |
| title_full_unstemmed | Screening Procedure for Hemihypertrophy: Preliminary Results of International Multicenter Prospective Study |
| title_short | Screening Procedure for Hemihypertrophy: Preliminary Results of International Multicenter Prospective Study |
| title_sort | screening procedure for hemihypertrophy preliminary results of international multicenter prospective study |
| topic | Hemihypertrophy Hemihyperplasia Asymmetric regional body overgrowth Body asymmetry Adolescents |
| url | http://cajgh.pitt.edu/ojs/index.php/cajgh/article/view/336 |
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