Change of the indices of the cytokine status in patients with chronic combined hepatitis B+C in a process of antiviral therapy
The author studied the cytokine status in patients with chronic combined hepatitis B+C in a process of antiviral therapy. The examination embraced 49 patients aged from 18 to 47 years (pegylated interferon- alfa2а and ribavirin were used in 24 patients). It is established, that a significant increas...
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Format: | Article |
Language: | Russian |
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Journal Infectology
2014-09-01
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Series: | Журнал инфектологии |
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Online Access: | https://journal.niidi.ru/jofin/article/view/25 |
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author | O. L. Sobolevskaya |
author_facet | O. L. Sobolevskaya |
author_sort | O. L. Sobolevskaya |
collection | DOAJ |
description | The author studied the cytokine status in patients with chronic combined hepatitis B+C in a process of antiviral therapy. The examination embraced 49 patients aged from 18 to 47 years (pegylated interferon- alfa2а and ribavirin were used in 24 patients). It is established, that a significant increase of the interferon-α, interferon-γ, tumor necrosis factor-α (with following decrease of tumor necrosis factor-α) in blood serum content in patients with a stable virusologic response serves as an early criterion of the antiviral therapy effectiveness. |
first_indexed | 2024-03-12T04:46:16Z |
format | Article |
id | doaj.art-b46787957c8a425fb300128fdb7bad29 |
institution | Directory Open Access Journal |
issn | 2072-6732 |
language | Russian |
last_indexed | 2025-03-14T08:37:19Z |
publishDate | 2014-09-01 |
publisher | Journal Infectology |
record_format | Article |
series | Журнал инфектологии |
spelling | doaj.art-b46787957c8a425fb300128fdb7bad292025-03-02T13:00:22ZrusJournal InfectologyЖурнал инфектологии2072-67322014-09-0132687310.22625/2072-6732-2011-3-2-68-7339Change of the indices of the cytokine status in patients with chronic combined hepatitis B+C in a process of antiviral therapyO. L. Sobolevskaya0Nizhegorodskaya State Medical Academy, Nizhniy NovgorodThe author studied the cytokine status in patients with chronic combined hepatitis B+C in a process of antiviral therapy. The examination embraced 49 patients aged from 18 to 47 years (pegylated interferon- alfa2а and ribavirin were used in 24 patients). It is established, that a significant increase of the interferon-α, interferon-γ, tumor necrosis factor-α (with following decrease of tumor necrosis factor-α) in blood serum content in patients with a stable virusologic response serves as an early criterion of the antiviral therapy effectiveness.https://journal.niidi.ru/jofin/article/view/25chronic combined hepatitis b+ccytokinesantiviral therapy |
spellingShingle | O. L. Sobolevskaya Change of the indices of the cytokine status in patients with chronic combined hepatitis B+C in a process of antiviral therapy Журнал инфектологии chronic combined hepatitis b+c cytokines antiviral therapy |
title | Change of the indices of the cytokine status in patients with chronic combined hepatitis B+C in a process of antiviral therapy |
title_full | Change of the indices of the cytokine status in patients with chronic combined hepatitis B+C in a process of antiviral therapy |
title_fullStr | Change of the indices of the cytokine status in patients with chronic combined hepatitis B+C in a process of antiviral therapy |
title_full_unstemmed | Change of the indices of the cytokine status in patients with chronic combined hepatitis B+C in a process of antiviral therapy |
title_short | Change of the indices of the cytokine status in patients with chronic combined hepatitis B+C in a process of antiviral therapy |
title_sort | change of the indices of the cytokine status in patients with chronic combined hepatitis b c in a process of antiviral therapy |
topic | chronic combined hepatitis b+c cytokines antiviral therapy |
url | https://journal.niidi.ru/jofin/article/view/25 |
work_keys_str_mv | AT olsobolevskaya changeoftheindicesofthecytokinestatusinpatientswithchroniccombinedhepatitisbcinaprocessofantiviraltherapy |