Silencing of HEPN1 is Responsible for the Aggressive Biological Behavior of Pituitary Somatotroph Adenomas

Silencing of HEPN1 is Responsible for the Aggressive Biological Behavior of Pituitary Somatotroph Adenomas

Background/Aims: The pathogenic mechanisms underlying pituitary adenoma formation, progression, and invasion are poorly understood. To identify candidate tumor suppressor genes, we selected somatotroph adenomas as representative of pituitary adenomas. Methods/Results: We used genome-wide differentia...

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Bibliographic Details
Main Authors: Hu Peng, Jingping Fan, Jian Wu, Juntian Lang, Junyu Wang, Huanhai Liu, Shuwei Zhao, Jianchun Liao
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2013-03-01
Series:Cellular Physiology and Biochemistry
Subjects:
HEPN1
Pituitary somatotroph adenomas
Invasion
Apoptosis
Proliferation
Online Access:http://www.karger.com/Article/FullText/343375

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