One-Pot Synthesis of MnO<sub>x</sub>-SiO<sub>2</sub> Porous Composites as Nanozymes with ROS-Scavenging Properties
The development of nanomaterials that mimic the activity of enzymes is a topic of interest, for the decomposition of reactive oxygen species (ROS). We report the preparation of a novel nanocomposite of MnO<sub>x</sub> needles covered with SiO<sub>2</sub> porous material. The...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2022-10-01
|
| Series: | Nanomaterials |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2079-4991/12/19/3503 |
| _version_ | 1797477676807618560 |
|---|---|
| author | M. Dolores Garrido Jamal El Haskouri María D. Marcos Francisco Pérez-Pla José Vicente Ros-Lis Pedro Amorós |
| author_facet | M. Dolores Garrido Jamal El Haskouri María D. Marcos Francisco Pérez-Pla José Vicente Ros-Lis Pedro Amorós |
| author_sort | M. Dolores Garrido |
| collection | DOAJ |
| description | The development of nanomaterials that mimic the activity of enzymes is a topic of interest, for the decomposition of reactive oxygen species (ROS). We report the preparation of a novel nanocomposite of MnO<sub>x</sub> needles covered with SiO<sub>2</sub> porous material. The material was prepared in one pot with a two-step procedure. The material was characterized by EDX, SEM, TEM, XRD, nitrogen adsorption–desorption isotherms, and XPS. The synthesis protocol took advantage of the atrane method, favoring the nucleation and initial growth of manganese oxide needles that remained embedded and homogeneously dispersed in a mesoporous silica matrix. The final composite had a high concentration of Mn (Si/Mn molar ratio of ca. 1). The nanozyme presented bimodal porosity: intraparticle and interparticle association with the surfactant micelles and the gaps between silica particles and MnO<sub>x</sub> needles, respectively. The porosity favored the migration of the reagent to the surface of the catalytic MnO<sub>x</sub>. The nanozyme showed very efficient SOD and catalase activities, thus improving other materials previously described. The kinetics were studied in detail, and the reaction mechanisms were proposed. It was shown that silica does not play an innocent role in the case of catalase activity, increasing the reaction rate. |
| first_indexed | 2024-03-09T21:21:06Z |
| format | Article |
| id | doaj.art-b46a6d6bd4914007b382221534044b26 |
| institution | Directory Open Access Journal |
| issn | 2079-4991 |
| language | English |
| last_indexed | 2024-03-09T21:21:06Z |
| publishDate | 2022-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Nanomaterials |
| spelling | doaj.art-b46a6d6bd4914007b382221534044b262023-11-23T21:21:10ZengMDPI AGNanomaterials2079-49912022-10-011219350310.3390/nano12193503One-Pot Synthesis of MnO<sub>x</sub>-SiO<sub>2</sub> Porous Composites as Nanozymes with ROS-Scavenging PropertiesM. Dolores Garrido0Jamal El Haskouri1María D. Marcos2Francisco Pérez-Pla3José Vicente Ros-Lis4Pedro Amorós5Institut de Ciència dels Materials (ICMUV), Universitat de València, Catedrático José Beltrán 2, 46980 Paterna, SpainInstitut de Ciència dels Materials (ICMUV), Universitat de València, Catedrático José Beltrán 2, 46980 Paterna, SpainCentro de Reconocimiento Molecular y Desarrollo Tecnológico (IDM), Unidad Mixta Universitat Politècnica de Valencia, Universitat de València, Departamento de Química, Universitat Politècnica de Valencia, 46022 Valencia, SpainInstitut de Ciència dels Materials (ICMUV), Universitat de València, Catedrático José Beltrán 2, 46980 Paterna, SpainCentro de Reconocimiento Molecular y Desarrollo Tecnológico (IDM), Unidad Mixta Universitat Politècnica de Valencia, Universitat de València, Departamento de Química Inorgánica, Universitat de València, Doctor Moliner 56, 46100 Valencia, SpainInstitut de Ciència dels Materials (ICMUV), Universitat de València, Catedrático José Beltrán 2, 46980 Paterna, SpainThe development of nanomaterials that mimic the activity of enzymes is a topic of interest, for the decomposition of reactive oxygen species (ROS). We report the preparation of a novel nanocomposite of MnO<sub>x</sub> needles covered with SiO<sub>2</sub> porous material. The material was prepared in one pot with a two-step procedure. The material was characterized by EDX, SEM, TEM, XRD, nitrogen adsorption–desorption isotherms, and XPS. The synthesis protocol took advantage of the atrane method, favoring the nucleation and initial growth of manganese oxide needles that remained embedded and homogeneously dispersed in a mesoporous silica matrix. The final composite had a high concentration of Mn (Si/Mn molar ratio of ca. 1). The nanozyme presented bimodal porosity: intraparticle and interparticle association with the surfactant micelles and the gaps between silica particles and MnO<sub>x</sub> needles, respectively. The porosity favored the migration of the reagent to the surface of the catalytic MnO<sub>x</sub>. The nanozyme showed very efficient SOD and catalase activities, thus improving other materials previously described. The kinetics were studied in detail, and the reaction mechanisms were proposed. It was shown that silica does not play an innocent role in the case of catalase activity, increasing the reaction rate.https://www.mdpi.com/2079-4991/12/19/3503nanozymemanganese oxidessilicamesoporouscatalasesuperoxide dismutase |
| spellingShingle | M. Dolores Garrido Jamal El Haskouri María D. Marcos Francisco Pérez-Pla José Vicente Ros-Lis Pedro Amorós One-Pot Synthesis of MnO<sub>x</sub>-SiO<sub>2</sub> Porous Composites as Nanozymes with ROS-Scavenging Properties Nanomaterials nanozyme manganese oxides silica mesoporous catalase superoxide dismutase |
| title | One-Pot Synthesis of MnO<sub>x</sub>-SiO<sub>2</sub> Porous Composites as Nanozymes with ROS-Scavenging Properties |
| title_full | One-Pot Synthesis of MnO<sub>x</sub>-SiO<sub>2</sub> Porous Composites as Nanozymes with ROS-Scavenging Properties |
| title_fullStr | One-Pot Synthesis of MnO<sub>x</sub>-SiO<sub>2</sub> Porous Composites as Nanozymes with ROS-Scavenging Properties |
| title_full_unstemmed | One-Pot Synthesis of MnO<sub>x</sub>-SiO<sub>2</sub> Porous Composites as Nanozymes with ROS-Scavenging Properties |
| title_short | One-Pot Synthesis of MnO<sub>x</sub>-SiO<sub>2</sub> Porous Composites as Nanozymes with ROS-Scavenging Properties |
| title_sort | one pot synthesis of mno sub x sub sio sub 2 sub porous composites as nanozymes with ros scavenging properties |
| topic | nanozyme manganese oxides silica mesoporous catalase superoxide dismutase |
| url | https://www.mdpi.com/2079-4991/12/19/3503 |
| work_keys_str_mv | AT mdoloresgarrido onepotsynthesisofmnosubxsubsiosub2subporouscompositesasnanozymeswithrosscavengingproperties AT jamalelhaskouri onepotsynthesisofmnosubxsubsiosub2subporouscompositesasnanozymeswithrosscavengingproperties AT mariadmarcos onepotsynthesisofmnosubxsubsiosub2subporouscompositesasnanozymeswithrosscavengingproperties AT franciscoperezpla onepotsynthesisofmnosubxsubsiosub2subporouscompositesasnanozymeswithrosscavengingproperties AT josevicenteroslis onepotsynthesisofmnosubxsubsiosub2subporouscompositesasnanozymeswithrosscavengingproperties AT pedroamoros onepotsynthesisofmnosubxsubsiosub2subporouscompositesasnanozymeswithrosscavengingproperties |