Protection of insect neurons by erythropoietin/CRLF3-mediated regulation of pro-apoptotic acetylcholinesterase
Abstract Cytokine receptor-like factor 3 (CRLF3) is a conserved but largely uncharacterized orphan cytokine receptor of eumetazoan animals. CRLF3-mediated neuroprotection in insects can be stimulated with human erythropoietin. To identify mechanisms of CRLF3-mediated neuroprotection we studied the e...
Main Authors: | Debbra Y. Knorr, Kristin Schneider, Luca Büschgens, Jan Förster, Nadine S. Georges, Bart R. H. Geurten, Ralf Heinrich |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2022-11-01
|
Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-022-22035-0 |
Similar Items
-
The cytokine receptor CRLF3 is a human neuroprotective EV-3 (Epo) receptor
by: Debbra Y. Knorr, et al.
Published: (2023-04-01) -
CRLF1 and CLCF1 in Development, Health and Disease
by: Laura Crisponi, et al.
Published: (2022-01-01) -
P344: ONCOGENESIS OF CRLF2 OVEREXPRESSION AND EFFECT OF A NOVEL JAK2 INHIBITOR IN CRLF2 OVEREXPRESSED B-CELL ACUTE LYMPHOBLASTIC LEUKEMIA
by: Yan Gu, et al.
Published: (2023-08-01) -
CRLF2 expression associates with ICN1 stabilization in T-cell acute lymphoblastic leukemia
by: Maciel, ALT, et al.
Published: (2019) -
Cytokine Receptor-Like Factor 3 (CRLF3) Contributes to Early Zebrafish Hematopoiesis
by: Tarannum Taznin, et al.
Published: (2022-06-01)