The combination of RPA-CRISPR/Cas12a and Leptospira IgM RDT enhances the early detection of leptospirosis.

The combination of RPA-CRISPR/Cas12a and Leptospira IgM RDT enhances the early detection of leptospirosis.

<h4>Background</h4>Lack of available sensitive point-of-care testing is one of the primary obstacles to the rapid diagnosis of leptospirosis. The purpose of this study was to test the performance of two point-of-care tests, a clustered regularly interspaced short palindromic repeat (CRIS...

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Main Authors: Sirawit Jirawannaporn, Umaporn Limothai, Sasipha Tachaboon, Janejira Dinhuzen, Patcharakorn Kiatamornrak, Watchadaporn Chaisuriyong, Nattachai Srisawat
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-08-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://journals.plos.org/plosntds/article/file?id=10.1371/journal.pntd.0011596&type=printable

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