| Summary: | Until recently, it was believed that the effects of probiotics are limited to a certain range of specific effects, but more and more studies indicate that their action on the host organism is more complex and systemic. Such effects interference of probiotics in the regulation of various pathways in the host organism. Systemic effect does not mean the sum of many minor impacts but precisely targeted impact on the most sensitive points or metabolic pathways. That allows to achieve a more significant effect in small doses through a cascade of reactions. In this case, probiotics can act both through the effect on other symbiont bacteria and directly on the host. One of the agents of such interactions can be oligopeptides of nonribosomal origin.
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