In vitro cell stretching devices and their applications: From cardiomyogenic differentiation to tissue engineering
Mechanical stretch plays an important role in the control of cardiomyocyte behavior, as well as in the study of the mechanisms of cardiovascular function and pathology. The complexity involved in biological systems in vivo has created a need for better in vitro techniques, thus a variety of cell str...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2023-06-01
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| Series: | Medicine in Novel Technology and Devices |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2590093523000152 |
| _version_ | 1797790851191013376 |
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| author | Jiangtao Zhao Fanzhe Meng Jiayi Qian Yan Huang Yubo Fan |
| author_facet | Jiangtao Zhao Fanzhe Meng Jiayi Qian Yan Huang Yubo Fan |
| author_sort | Jiangtao Zhao |
| collection | DOAJ |
| description | Mechanical stretch plays an important role in the control of cardiomyocyte behavior, as well as in the study of the mechanisms of cardiovascular function and pathology. The complexity involved in biological systems in vivo has created a need for better in vitro techniques, thus a variety of cell stretching devices have been developed for a deeper understanding of cellular responses to strain. In this review, we introduce the design, functionality, and characteristics of multiple types of cell stretching devices from two and three dimensions, then discuss the research progress of promoting cardiomyogenic differentiation of stem cells by external stretching and its application in cardiac tissue engineering. |
| first_indexed | 2024-03-13T02:10:24Z |
| format | Article |
| id | doaj.art-b4783928eb8b4641ad4e4913e1e33435 |
| institution | Directory Open Access Journal |
| issn | 2590-0935 |
| language | English |
| last_indexed | 2024-03-13T02:10:24Z |
| publishDate | 2023-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Medicine in Novel Technology and Devices |
| spelling | doaj.art-b4783928eb8b4641ad4e4913e1e334352023-07-01T04:35:33ZengElsevierMedicine in Novel Technology and Devices2590-09352023-06-0118100220In vitro cell stretching devices and their applications: From cardiomyogenic differentiation to tissue engineeringJiangtao Zhao0Fanzhe Meng1Jiayi Qian2Yan Huang3Yubo Fan4Key Laboratory of Biomechanics and Mechanobiology (Beihang University), Ministry of Education, Beijing Advanced Innovation Center for Biomedical Engineering, School of Biological Science and Medical Engineering, Beihang University, Beijing, 100083, ChinaKey Laboratory of Biomechanics and Mechanobiology (Beihang University), Ministry of Education, Beijing Advanced Innovation Center for Biomedical Engineering, School of Biological Science and Medical Engineering, Beihang University, Beijing, 100083, ChinaKey Laboratory of Biomechanics and Mechanobiology (Beihang University), Ministry of Education, Beijing Advanced Innovation Center for Biomedical Engineering, School of Biological Science and Medical Engineering, Beihang University, Beijing, 100083, ChinaKey Laboratory of Biomechanics and Mechanobiology (Beihang University), Ministry of Education, Beijing Advanced Innovation Center for Biomedical Engineering, School of Biological Science and Medical Engineering, Beihang University, Beijing, 100083, China; Corresponding author. Key Laboratory of Biomechanics and Mechanobiology (Beihang University), Ministry of Education, Beijing Advanced Innovation Center for Biomedical Engineering, School of Biological Science and Medical Engineering, Beihang University, No.37, Xueyuan Road, Haidian district, Beijing, 100083, ChinaKey Laboratory of Biomechanics and Mechanobiology (Beihang University), Ministry of Education, Beijing Advanced Innovation Center for Biomedical Engineering, School of Biological Science and Medical Engineering, Beihang University, Beijing, 100083, China; School of Engineering Medicine, Beihang University, Beijing, 100083, China; Corresponding author.Key Laboratory of Biomechanics and Mechanobiology (Beihang University), Ministry of Education, Beijing Advanced Innovation Center for Biomedical Engineering, School of Biological Science and Medical Engineering, Beihang University, Beijing, 100083, ChinaMechanical stretch plays an important role in the control of cardiomyocyte behavior, as well as in the study of the mechanisms of cardiovascular function and pathology. The complexity involved in biological systems in vivo has created a need for better in vitro techniques, thus a variety of cell stretching devices have been developed for a deeper understanding of cellular responses to strain. In this review, we introduce the design, functionality, and characteristics of multiple types of cell stretching devices from two and three dimensions, then discuss the research progress of promoting cardiomyogenic differentiation of stem cells by external stretching and its application in cardiac tissue engineering.http://www.sciencedirect.com/science/article/pii/S2590093523000152Mechanical stretchin vitro devicesStem cellCardiomyogenic differentiationHydrogels |
| spellingShingle | Jiangtao Zhao Fanzhe Meng Jiayi Qian Yan Huang Yubo Fan In vitro cell stretching devices and their applications: From cardiomyogenic differentiation to tissue engineering Medicine in Novel Technology and Devices Mechanical stretch in vitro devices Stem cell Cardiomyogenic differentiation Hydrogels |
| title | In vitro cell stretching devices and their applications: From cardiomyogenic differentiation to tissue engineering |
| title_full | In vitro cell stretching devices and their applications: From cardiomyogenic differentiation to tissue engineering |
| title_fullStr | In vitro cell stretching devices and their applications: From cardiomyogenic differentiation to tissue engineering |
| title_full_unstemmed | In vitro cell stretching devices and their applications: From cardiomyogenic differentiation to tissue engineering |
| title_short | In vitro cell stretching devices and their applications: From cardiomyogenic differentiation to tissue engineering |
| title_sort | in vitro cell stretching devices and their applications from cardiomyogenic differentiation to tissue engineering |
| topic | Mechanical stretch in vitro devices Stem cell Cardiomyogenic differentiation Hydrogels |
| url | http://www.sciencedirect.com/science/article/pii/S2590093523000152 |
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