PP 8.1 – 00003 Optimization of the 5′ cap and untranslated regions enhances the immunogenicity of an mRNA-based therapeutic vaccine in SIV-infected rhesus macaques on ART

Bibliographic Details
Main Authors: W. Omange, B. Varco-Merth, A. Morenco, M.T. Chaunzwa, C. Nkoy, D. Duell, O. Fadeyi, M. Medina, S. Hoffmeister, W. Goodwin, R. Butler, Z. Etaki, H. Park, J. Smedley, M.K. Axhelm, S. Hansen, J. Lifson, J. Gergen, S. Rauch, B. Petsch, L.J. Picker, A.A. Okoye
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Journal of Virus Eradication
Online Access:http://www.sciencedirect.com/science/article/pii/S2055664022002199
_version_ 1828262854749323264
author W. Omange
B. Varco-Merth
A. Morenco
M.T. Chaunzwa
C. Nkoy
D. Duell
O. Fadeyi
M. Medina
S. Hoffmeister
W. Goodwin
R. Butler
Z. Etaki
H. Park
J. Smedley
M.K. Axhelm
S. Hansen
J. Lifson
J. Gergen
S. Rauch
B. Petsch
L.J. Picker
A.A. Okoye
author_facet W. Omange
B. Varco-Merth
A. Morenco
M.T. Chaunzwa
C. Nkoy
D. Duell
O. Fadeyi
M. Medina
S. Hoffmeister
W. Goodwin
R. Butler
Z. Etaki
H. Park
J. Smedley
M.K. Axhelm
S. Hansen
J. Lifson
J. Gergen
S. Rauch
B. Petsch
L.J. Picker
A.A. Okoye
author_sort W. Omange
collection DOAJ
first_indexed 2024-04-13T04:02:34Z
format Article
id doaj.art-b478cb703b5b473ea6702724b20b8a83
institution Directory Open Access Journal
issn 2055-6640
language English
last_indexed 2024-04-13T04:02:34Z
publishDate 2022-12-01
publisher Elsevier
record_format Article
series Journal of Virus Eradication
spelling doaj.art-b478cb703b5b473ea6702724b20b8a832022-12-22T03:03:25ZengElsevierJournal of Virus Eradication2055-66402022-12-018100281PP 8.1 – 00003 Optimization of the 5′ cap and untranslated regions enhances the immunogenicity of an mRNA-based therapeutic vaccine in SIV-infected rhesus macaques on ARTW. Omange0B. Varco-Merth1A. Morenco2M.T. Chaunzwa3C. Nkoy4D. Duell5O. Fadeyi6M. Medina7S. Hoffmeister8W. Goodwin9R. Butler10Z. Etaki11H. Park12J. Smedley13M.K. Axhelm14S. Hansen15J. Lifson16J. Gergen17S. Rauch18B. Petsch19L.J. Picker20A.A. Okoye21Vaccine and Gene therapy Institute, Oregon Health and Science University, Beaverton, Oregon, USAVaccine and Gene therapy Institute, Oregon Health and Science University, Beaverton, Oregon, USA; Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon, USAVaccine and Gene therapy Institute, Oregon Health and Science University, Beaverton, Oregon, USA; Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon, USAVaccine and Gene therapy Institute, Oregon Health and Science University, Beaverton, Oregon, USA; Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon, USAVaccine and Gene therapy Institute, Oregon Health and Science University, Beaverton, Oregon, USA; Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon, USAVaccine and Gene therapy Institute, Oregon Health and Science University, Beaverton, Oregon, USA; Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon, USAVaccine and Gene therapy Institute, Oregon Health and Science University, Beaverton, Oregon, USA; Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon, USAVaccine and Gene therapy Institute, Oregon Health and Science University, Beaverton, Oregon, USA; Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon, USAVaccine and Gene therapy Institute, Oregon Health and Science University, Beaverton, Oregon, USA; Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon, USAVaccine and Gene therapy Institute, Oregon Health and Science University, Beaverton, Oregon, USA; Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon, USAVaccine and Gene therapy Institute, Oregon Health and Science University, Beaverton, Oregon, USA; Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon, USAVaccine and Gene therapy Institute, Oregon Health and Science University, Beaverton, Oregon, USA; Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon, USAVaccine and Gene therapy Institute, Oregon Health and Science University, Beaverton, Oregon, USA; Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon, USAOregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon, USAOregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon, USAVaccine and Gene therapy Institute, Oregon Health and Science University, Beaverton, Oregon, USA; Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon, USAAIDS and Cancer Virus Program, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, Maryland, USACureVac AG, Tübingen, GermanyCureVac AG, Tübingen, GermanyCureVac AG, Tübingen, GermanyVaccine and Gene therapy Institute, Oregon Health and Science University, Beaverton, Oregon, USA; Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon, USAVaccine and Gene therapy Institute, Oregon Health and Science University, Beaverton, Oregon, USA; Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon, USAhttp://www.sciencedirect.com/science/article/pii/S2055664022002199
spellingShingle W. Omange
B. Varco-Merth
A. Morenco
M.T. Chaunzwa
C. Nkoy
D. Duell
O. Fadeyi
M. Medina
S. Hoffmeister
W. Goodwin
R. Butler
Z. Etaki
H. Park
J. Smedley
M.K. Axhelm
S. Hansen
J. Lifson
J. Gergen
S. Rauch
B. Petsch
L.J. Picker
A.A. Okoye
PP 8.1 – 00003 Optimization of the 5′ cap and untranslated regions enhances the immunogenicity of an mRNA-based therapeutic vaccine in SIV-infected rhesus macaques on ART
Journal of Virus Eradication
title PP 8.1 – 00003 Optimization of the 5′ cap and untranslated regions enhances the immunogenicity of an mRNA-based therapeutic vaccine in SIV-infected rhesus macaques on ART
title_full PP 8.1 – 00003 Optimization of the 5′ cap and untranslated regions enhances the immunogenicity of an mRNA-based therapeutic vaccine in SIV-infected rhesus macaques on ART
title_fullStr PP 8.1 – 00003 Optimization of the 5′ cap and untranslated regions enhances the immunogenicity of an mRNA-based therapeutic vaccine in SIV-infected rhesus macaques on ART
title_full_unstemmed PP 8.1 – 00003 Optimization of the 5′ cap and untranslated regions enhances the immunogenicity of an mRNA-based therapeutic vaccine in SIV-infected rhesus macaques on ART
title_short PP 8.1 – 00003 Optimization of the 5′ cap and untranslated regions enhances the immunogenicity of an mRNA-based therapeutic vaccine in SIV-infected rhesus macaques on ART
title_sort pp 8 1 00003 optimization of the 5 cap and untranslated regions enhances the immunogenicity of an mrna based therapeutic vaccine in siv infected rhesus macaques on art
url http://www.sciencedirect.com/science/article/pii/S2055664022002199
work_keys_str_mv AT womange pp8100003optimizationofthe5capanduntranslatedregionsenhancestheimmunogenicityofanmrnabasedtherapeuticvaccineinsivinfectedrhesusmacaquesonart
AT bvarcomerth pp8100003optimizationofthe5capanduntranslatedregionsenhancestheimmunogenicityofanmrnabasedtherapeuticvaccineinsivinfectedrhesusmacaquesonart
AT amorenco pp8100003optimizationofthe5capanduntranslatedregionsenhancestheimmunogenicityofanmrnabasedtherapeuticvaccineinsivinfectedrhesusmacaquesonart
AT mtchaunzwa pp8100003optimizationofthe5capanduntranslatedregionsenhancestheimmunogenicityofanmrnabasedtherapeuticvaccineinsivinfectedrhesusmacaquesonart
AT cnkoy pp8100003optimizationofthe5capanduntranslatedregionsenhancestheimmunogenicityofanmrnabasedtherapeuticvaccineinsivinfectedrhesusmacaquesonart
AT dduell pp8100003optimizationofthe5capanduntranslatedregionsenhancestheimmunogenicityofanmrnabasedtherapeuticvaccineinsivinfectedrhesusmacaquesonart
AT ofadeyi pp8100003optimizationofthe5capanduntranslatedregionsenhancestheimmunogenicityofanmrnabasedtherapeuticvaccineinsivinfectedrhesusmacaquesonart
AT mmedina pp8100003optimizationofthe5capanduntranslatedregionsenhancestheimmunogenicityofanmrnabasedtherapeuticvaccineinsivinfectedrhesusmacaquesonart
AT shoffmeister pp8100003optimizationofthe5capanduntranslatedregionsenhancestheimmunogenicityofanmrnabasedtherapeuticvaccineinsivinfectedrhesusmacaquesonart
AT wgoodwin pp8100003optimizationofthe5capanduntranslatedregionsenhancestheimmunogenicityofanmrnabasedtherapeuticvaccineinsivinfectedrhesusmacaquesonart
AT rbutler pp8100003optimizationofthe5capanduntranslatedregionsenhancestheimmunogenicityofanmrnabasedtherapeuticvaccineinsivinfectedrhesusmacaquesonart
AT zetaki pp8100003optimizationofthe5capanduntranslatedregionsenhancestheimmunogenicityofanmrnabasedtherapeuticvaccineinsivinfectedrhesusmacaquesonart
AT hpark pp8100003optimizationofthe5capanduntranslatedregionsenhancestheimmunogenicityofanmrnabasedtherapeuticvaccineinsivinfectedrhesusmacaquesonart
AT jsmedley pp8100003optimizationofthe5capanduntranslatedregionsenhancestheimmunogenicityofanmrnabasedtherapeuticvaccineinsivinfectedrhesusmacaquesonart
AT mkaxhelm pp8100003optimizationofthe5capanduntranslatedregionsenhancestheimmunogenicityofanmrnabasedtherapeuticvaccineinsivinfectedrhesusmacaquesonart
AT shansen pp8100003optimizationofthe5capanduntranslatedregionsenhancestheimmunogenicityofanmrnabasedtherapeuticvaccineinsivinfectedrhesusmacaquesonart
AT jlifson pp8100003optimizationofthe5capanduntranslatedregionsenhancestheimmunogenicityofanmrnabasedtherapeuticvaccineinsivinfectedrhesusmacaquesonart
AT jgergen pp8100003optimizationofthe5capanduntranslatedregionsenhancestheimmunogenicityofanmrnabasedtherapeuticvaccineinsivinfectedrhesusmacaquesonart
AT srauch pp8100003optimizationofthe5capanduntranslatedregionsenhancestheimmunogenicityofanmrnabasedtherapeuticvaccineinsivinfectedrhesusmacaquesonart
AT bpetsch pp8100003optimizationofthe5capanduntranslatedregionsenhancestheimmunogenicityofanmrnabasedtherapeuticvaccineinsivinfectedrhesusmacaquesonart
AT ljpicker pp8100003optimizationofthe5capanduntranslatedregionsenhancestheimmunogenicityofanmrnabasedtherapeuticvaccineinsivinfectedrhesusmacaquesonart
AT aaokoye pp8100003optimizationofthe5capanduntranslatedregionsenhancestheimmunogenicityofanmrnabasedtherapeuticvaccineinsivinfectedrhesusmacaquesonart