Novel BRD2::NUTM1 Fusion in NUT Carcinoma With Exceptional Response to Chemotherapy: A Case Report

Novel BRD2::NUTM1 Fusion in NUT Carcinoma With Exceptional Response to Chemotherapy: A Case Report

We present the first known case of a patient with BRD2::NUTM1-driven NUT carcinoma. A 59-year-old woman presented with poorly differentiated squamous cell lung cancer metastatic to the pleura. Eventually, a positive NUT immunohistochemistry, NUT fluorescence in situ hybridization, and RNA next-gener...

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Bibliographic Details
Main Authors: Sarah J. Wu, MD, PhD, Justin J. Kim, Yeying Huang, BS, R. Taylor Durall, BS, Simone Becker, RN, Stephanie Canty, CNP, MSN, Stefania Molinaro, BS, Evan Pisick, MD, Geoffrey I. Shapiro, MD, PhD, Christopher A. French, MD, Jia Luo, MD
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:JTO Clinical and Research Reports
Subjects:
Case report
NUT carcinoma
BRD2::NUTM1 gene fusion
Non–small cell lung cancer
Online Access:http://www.sciencedirect.com/science/article/pii/S2666364323001686

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