Revisiting the role of sulfated oxides for the synthesis of pharmaceutically important heterocycles: Understanding, challenges, and future prospects
The development of sustainable catalytic processes is the requirement of the future to replace traditional protocols involving hazardous, non-green, non-benign reagents/solvents, and cost ineffectiveness. Metal and mixed metal oxides due to their redox properties make them potential substitutes for...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2023-12-01
|
| Series: | Tetrahedron Green Chem |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2773223123000304 |
| _version_ | 1797342119678967808 |
|---|---|
| author | Sandeep S. Kahandal Anand S. Burange Thomson A. Fernandes |
| author_facet | Sandeep S. Kahandal Anand S. Burange Thomson A. Fernandes |
| author_sort | Sandeep S. Kahandal |
| collection | DOAJ |
| description | The development of sustainable catalytic processes is the requirement of the future to replace traditional protocols involving hazardous, non-green, non-benign reagents/solvents, and cost ineffectiveness. Metal and mixed metal oxides due to their redox properties make them potential substitutes for conventional homogeneous catalysts. The acidity can be enhanced further by the sulfation process to form sulfated oxides representing a new class of solid acid catalysts. This review is the revisiting of sulfated solid acid catalysts, with major emphasis on understanding, methods, applications, and their role in the syntheses of heterocycles of pharmaceutical importance. The present review also discusses factors affecting the acidity of the catalysts, possibilities of leaching in reaction media, methods of sulfation to arrest leaching, other challenges, and future prospects. |
| first_indexed | 2024-03-08T10:28:49Z |
| format | Article |
| id | doaj.art-b47c6b4fefa04bcca838d873126c8878 |
| institution | Directory Open Access Journal |
| issn | 2773-2231 |
| language | English |
| last_indexed | 2024-03-08T10:28:49Z |
| publishDate | 2023-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Tetrahedron Green Chem |
| spelling | doaj.art-b47c6b4fefa04bcca838d873126c88782024-01-27T07:03:23ZengElsevierTetrahedron Green Chem2773-22312023-12-012100031Revisiting the role of sulfated oxides for the synthesis of pharmaceutically important heterocycles: Understanding, challenges, and future prospectsSandeep S. Kahandal0Anand S. Burange1Thomson A. Fernandes2Department of Chemistry, V.P.M.'s B. N. Bandodkar College of Science, (Autonomous), Thane, Maharashtra, 400601, India; Corresponding author.Department of Chemistry, John Wilson Education Society's, Wilson College (Autonomous), Mumbai, Maharashtra, 400007, India; Corresponding author.Department of Chemistry, John Wilson Education Society's, Wilson College (Autonomous), Mumbai, Maharashtra, 400007, IndiaThe development of sustainable catalytic processes is the requirement of the future to replace traditional protocols involving hazardous, non-green, non-benign reagents/solvents, and cost ineffectiveness. Metal and mixed metal oxides due to their redox properties make them potential substitutes for conventional homogeneous catalysts. The acidity can be enhanced further by the sulfation process to form sulfated oxides representing a new class of solid acid catalysts. This review is the revisiting of sulfated solid acid catalysts, with major emphasis on understanding, methods, applications, and their role in the syntheses of heterocycles of pharmaceutical importance. The present review also discusses factors affecting the acidity of the catalysts, possibilities of leaching in reaction media, methods of sulfation to arrest leaching, other challenges, and future prospects.http://www.sciencedirect.com/science/article/pii/S2773223123000304ZirconiaBenzodiazepineBiginelliRedoxCatalysis |
| spellingShingle | Sandeep S. Kahandal Anand S. Burange Thomson A. Fernandes Revisiting the role of sulfated oxides for the synthesis of pharmaceutically important heterocycles: Understanding, challenges, and future prospects Tetrahedron Green Chem Zirconia Benzodiazepine Biginelli Redox Catalysis |
| title | Revisiting the role of sulfated oxides for the synthesis of pharmaceutically important heterocycles: Understanding, challenges, and future prospects |
| title_full | Revisiting the role of sulfated oxides for the synthesis of pharmaceutically important heterocycles: Understanding, challenges, and future prospects |
| title_fullStr | Revisiting the role of sulfated oxides for the synthesis of pharmaceutically important heterocycles: Understanding, challenges, and future prospects |
| title_full_unstemmed | Revisiting the role of sulfated oxides for the synthesis of pharmaceutically important heterocycles: Understanding, challenges, and future prospects |
| title_short | Revisiting the role of sulfated oxides for the synthesis of pharmaceutically important heterocycles: Understanding, challenges, and future prospects |
| title_sort | revisiting the role of sulfated oxides for the synthesis of pharmaceutically important heterocycles understanding challenges and future prospects |
| topic | Zirconia Benzodiazepine Biginelli Redox Catalysis |
| url | http://www.sciencedirect.com/science/article/pii/S2773223123000304 |
| work_keys_str_mv | AT sandeepskahandal revisitingtheroleofsulfatedoxidesforthesynthesisofpharmaceuticallyimportantheterocyclesunderstandingchallengesandfutureprospects AT anandsburange revisitingtheroleofsulfatedoxidesforthesynthesisofpharmaceuticallyimportantheterocyclesunderstandingchallengesandfutureprospects AT thomsonafernandes revisitingtheroleofsulfatedoxidesforthesynthesisofpharmaceuticallyimportantheterocyclesunderstandingchallengesandfutureprospects |