Neurological Manifestations in Pediatric COVID-19 Patients Hospitalized at King Abdulaziz University Hospital, Jeddah, Saudi Arabia: A Retrospective Study
There are limited data about neurological manifestations in pediatric COVID-19 patients from all over the world, including Saudi Arabia. This study was performed to identify characteristics of pediatric COVID-19 cases with neurologic involvement hospitalized at King Abdulaziz University Hospital (KA...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-11-01
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| Series: | Children |
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| Online Access: | https://www.mdpi.com/2227-9067/9/12/1870 |
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| author | Moustafa A. Hegazi Fajr A. Saeedi Ali F. Atwah Mohamed H. Sayed Asala A. Albeladi Shahad B. Alyoubi Razan A. Aljudibi Shahad M. Alyaslami Abdullah T. Alkathiry Abobakr A. Abdelgalil |
| author_facet | Moustafa A. Hegazi Fajr A. Saeedi Ali F. Atwah Mohamed H. Sayed Asala A. Albeladi Shahad B. Alyoubi Razan A. Aljudibi Shahad M. Alyaslami Abdullah T. Alkathiry Abobakr A. Abdelgalil |
| author_sort | Moustafa A. Hegazi |
| collection | DOAJ |
| description | There are limited data about neurological manifestations in pediatric COVID-19 patients from all over the world, including Saudi Arabia. This study was performed to identify characteristics of pediatric COVID-19 cases with neurologic involvement hospitalized at King Abdulaziz University Hospital (KAUH), Saudi Arabia. This retrospective cross-sectional study included hospitalized patients aged 0–19 years with confirmed SARS-CoV-2 from April 2020 to February 2022. The required data were retrieved from patients’ medical records. Ninety-four cases were included. The median ages of the studied group, those with neurological manifestations, and those without neurologic manifestations, were 6.5, 11.0, and 5.0 years, respectively. Neurological manifestations occurred in 29 COVID-19 patients (30.9%) with headache and decreased consciousness being the most common recorded manifestations in 8.5% and 6.4% of patients, respectively. Specific neurological manifestations were rare, as only two infants developed encephalopathy with fatal outcome. Most patients with and without neurological manifestations survived. Neuroimaging abnormalities were detected in 8 cases with neurological manifestations. Neurological manifestations were common in 31% of hospitalized pediatric COVID-19 cases. However, most of the neurological manifestations were mild and nonspecific, with headache being the most common one. Specific neurological manifestations were rare; however, pediatric COVID-19 patients, particularly young infants, were at risk of developing severe encephalopathy with fatal outcome. |
| first_indexed | 2024-03-09T17:11:44Z |
| format | Article |
| id | doaj.art-b47f7ce9e0e54ffaab91db4cbde30144 |
| institution | Directory Open Access Journal |
| issn | 2227-9067 |
| language | English |
| last_indexed | 2024-03-09T17:11:44Z |
| publishDate | 2022-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Children |
| spelling | doaj.art-b47f7ce9e0e54ffaab91db4cbde301442023-11-24T14:01:10ZengMDPI AGChildren2227-90672022-11-01912187010.3390/children9121870Neurological Manifestations in Pediatric COVID-19 Patients Hospitalized at King Abdulaziz University Hospital, Jeddah, Saudi Arabia: A Retrospective StudyMoustafa A. Hegazi0Fajr A. Saeedi1Ali F. Atwah2Mohamed H. Sayed3Asala A. Albeladi4Shahad B. Alyoubi5Razan A. Aljudibi6Shahad M. Alyaslami7Abdullah T. Alkathiry8Abobakr A. Abdelgalil9Department of Pediatrics, Faculty of Medicine in Rabigh, King Abdulaziz University, Jeddah 21589, Saudi ArabiaDepartment of Pediatrics, Faculty of Medicine in Rabigh, King Abdulaziz University, Jeddah 21589, Saudi ArabiaDepartment of Pediatrics, Faculty of Medicine in Rabigh, King Abdulaziz University, Jeddah 21589, Saudi ArabiaDepartment of Pediatrics, Faculty of Medicine in Rabigh, King Abdulaziz University, Jeddah 21589, Saudi ArabiaFaculty of Medicine in Rabigh, King Abdulaziz University, Jeddah 21589, Saudi ArabiaFaculty of Medicine in Rabigh, King Abdulaziz University, Jeddah 21589, Saudi ArabiaFaculty of Medicine in Rabigh, King Abdulaziz University, Jeddah 21589, Saudi ArabiaFaculty of Medicine in Rabigh, King Abdulaziz University, Jeddah 21589, Saudi ArabiaFaculty of Medicine in Rabigh, King Abdulaziz University, Jeddah 21589, Saudi ArabiaDepartment of Pediatrics, Faculty of Medicine, Cairo University, Cairo 12613, EgyptThere are limited data about neurological manifestations in pediatric COVID-19 patients from all over the world, including Saudi Arabia. This study was performed to identify characteristics of pediatric COVID-19 cases with neurologic involvement hospitalized at King Abdulaziz University Hospital (KAUH), Saudi Arabia. This retrospective cross-sectional study included hospitalized patients aged 0–19 years with confirmed SARS-CoV-2 from April 2020 to February 2022. The required data were retrieved from patients’ medical records. Ninety-four cases were included. The median ages of the studied group, those with neurological manifestations, and those without neurologic manifestations, were 6.5, 11.0, and 5.0 years, respectively. Neurological manifestations occurred in 29 COVID-19 patients (30.9%) with headache and decreased consciousness being the most common recorded manifestations in 8.5% and 6.4% of patients, respectively. Specific neurological manifestations were rare, as only two infants developed encephalopathy with fatal outcome. Most patients with and without neurological manifestations survived. Neuroimaging abnormalities were detected in 8 cases with neurological manifestations. Neurological manifestations were common in 31% of hospitalized pediatric COVID-19 cases. However, most of the neurological manifestations were mild and nonspecific, with headache being the most common one. Specific neurological manifestations were rare; however, pediatric COVID-19 patients, particularly young infants, were at risk of developing severe encephalopathy with fatal outcome.https://www.mdpi.com/2227-9067/9/12/1870neurological manifestationsclinical featuresoutcomehospitalized pediatric COVID-19Saudi Arabia |
| spellingShingle | Moustafa A. Hegazi Fajr A. Saeedi Ali F. Atwah Mohamed H. Sayed Asala A. Albeladi Shahad B. Alyoubi Razan A. Aljudibi Shahad M. Alyaslami Abdullah T. Alkathiry Abobakr A. Abdelgalil Neurological Manifestations in Pediatric COVID-19 Patients Hospitalized at King Abdulaziz University Hospital, Jeddah, Saudi Arabia: A Retrospective Study Children neurological manifestations clinical features outcome hospitalized pediatric COVID-19 Saudi Arabia |
| title | Neurological Manifestations in Pediatric COVID-19 Patients Hospitalized at King Abdulaziz University Hospital, Jeddah, Saudi Arabia: A Retrospective Study |
| title_full | Neurological Manifestations in Pediatric COVID-19 Patients Hospitalized at King Abdulaziz University Hospital, Jeddah, Saudi Arabia: A Retrospective Study |
| title_fullStr | Neurological Manifestations in Pediatric COVID-19 Patients Hospitalized at King Abdulaziz University Hospital, Jeddah, Saudi Arabia: A Retrospective Study |
| title_full_unstemmed | Neurological Manifestations in Pediatric COVID-19 Patients Hospitalized at King Abdulaziz University Hospital, Jeddah, Saudi Arabia: A Retrospective Study |
| title_short | Neurological Manifestations in Pediatric COVID-19 Patients Hospitalized at King Abdulaziz University Hospital, Jeddah, Saudi Arabia: A Retrospective Study |
| title_sort | neurological manifestations in pediatric covid 19 patients hospitalized at king abdulaziz university hospital jeddah saudi arabia a retrospective study |
| topic | neurological manifestations clinical features outcome hospitalized pediatric COVID-19 Saudi Arabia |
| url | https://www.mdpi.com/2227-9067/9/12/1870 |
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