LC–MS<sup>3</sup> Strategy for Quantification of Carbamazepine in Human Plasma and Its Application in Therapeutic Drug Monitoring

LC–MS<sup>3</sup> Strategy for Quantification of Carbamazepine in Human Plasma and Its Application in Therapeutic Drug Monitoring

This study developed a detection method based on the strategy of HPLC/MS<sup>3</sup> and verified its suitability by quantifying carbamazepine in human plasma. The high-performance liquid chromatography–tandem mass spectrometry (HPLC/MS<sup>3</sup>) system was performed using...

Full description

Bibliographic Details
Main Authors:	Dongxiao Ma, Zhengchao Ji, Haiwei Cao, Jing Huang, Lei Zeng, Lei Yin
Format:	Article
Language:	English
Published:	MDPI AG 2022-02-01
Series:	Molecules
Subjects:	LC-MS<sup>3</sup> carbamazepine therapeutic drug monitoring
Online Access:	https://www.mdpi.com/1420-3049/27/4/1224

Similar Items

Comparison of LC-MS<sup>3</sup> and LC-MRM Methods for Quantifying Amantadine and Its Application in Therapeutic Amantadine Monitoring in Human Plasma
by: Qiang Sun, et al.
Published: (2022-11-01)

Comparison of LC-MS<sup>3</sup> and LC-MRM Method for Quantifying Voriconazole and Its Application in Therapeutic Drug Monitoring of Human Plasma
by: Wenbo Ren, et al.
Published: (2022-08-01)

Simultaneous Determination of Carbamazepine and Carbamazepine-10,11-epoxide in Different Biological Matrices by LC-MS/MS
by: Andonie Dan, et al.
Published: (2017-09-01)

Development and Validation of a Highly Sensitive and Rapid LC-MS<sup>3</sup> Strategy to Determine Oxcarbazepine and Its Active Metabolite in the Serum of Patients with Epilepsy and Its Application in Therapeutic Drug Monitoring
by: Zhengchao Ji, et al.
Published: (2022-09-01)

Characterization of Polyester Coatings Intended for Food Contact by Different Analytical Techniques and Migration Testing by LC-MS<sup>n</sup>
by: Antía Lestido-Cardama, et al.
Published: (2022-01-01)

Characterization of Phytochemicals in Berry Fruit Wines Analyzed by Liquid Chromatography Coupled to Photodiode-Array Detection and Electrospray Ionization/Ion Trap Mass Spectrometry (LC-DAD-ESI-MS<sup>n</sup>) and Their Antioxidant and Antimicrobial Activity
by: Agata Czyżowska, et al.
Published: (2020-12-01)

Chicken Combs and Wattles as Sources of Bioactive Peptides: Optimization of Hydrolysis, Identification by LC-ESI-MS<sup>2</sup> and Bioactivity Assessment
by: Taliana Bezerra, et al.
Published: (2020-04-01)

Mapping m<sup>6</sup>A Sites on HIV-1 RNA Using Oligonucleotide LC-MS/MS
by: Alice Baek, et al.
Published: (2024-01-01)

Characterization in Inhibitory Effectiveness of Carbamazepine in Voltage-Gated Na<sup>+</sup> and Erg-Mediated K<sup>+</sup> Currents in a Mouse Neural Crest-Derived (Neuro-2a) Cell Line
by: Po-Ming Wu, et al.
Published: (2022-07-01)

A Simple, Fast, Sensitive LC-MS/MS Method to Quantify NAD(H) in Biological Samples: Plasma NAD(H) Measurement to Monitor Brain Pathophysiology
by: Tamaki Ishima, et al.
Published: (2024-02-01)

LC–MS/MS method for simultaneous quantification of ten antibiotics in human plasma for routine therapeutic drug monitoring
by: Mirjana Radovanovic, et al.
Published: (2022-11-01)

Extraction, Enrichment, and LC-MS<i><sup>n</sup></i>-Based Characterization of Phlorotannins and Related Phenolics from the Brown Seaweed, <i>Ascophyllum nodosum</i>
by: J. William Allwood, et al.
Published: (2020-08-01)

Liquid Chromatography Tandem Mass Spectrometry Quantification of <sup>13</sup>C-Labeling in Sugars
by: Jean-Christophe Cocuron, et al.
Published: (2020-01-01)

Chemical Separation of Uranium and Precise Measurement of <sup>234</sup>U/<sup>238</sup>U and <sup>235</sup>U/<sup>238</sup>U Ratios in Soil Samples Using Multi Collector Inductively Coupled Plasma Mass Spectrometry
by: Nimelan Veerasamy, et al.
Published: (2020-05-01)

Antioxidant and Antimicrobial Activities of <i>Erodium arborescens</i> Aerial Part Extracts and Characterization by LC-HESI-MS<sup>2</sup> of Its Acetone Extract
by: Sonda Samet, et al.
Published: (2022-07-01)

Simultaneous Determination of Phenobarbital, Phenytoin, Carbamazepine and Carbamazepine-10,11-epoxide in Plasma of Epileptic Patients
by: Azam Samadi, et al.
Published: (2019-12-01)

Analytical Methodology for a Metabolome Atlas of Goat’s Plasma, Milk and Feces Using <sup>1</sup>H-NMR and UHPLC-HRMS
by: Cécile Martias, et al.
Published: (2021-10-01)

Dried Plasma Spot Based LC–MS/MS Method for Monitoring of Meropenem in the Blood of Treated Patients
by: Haiwei Cao, et al.
Published: (2022-03-01)

Rapid Determination of Per- and Polyfluoroalkyl Substances (PFAS) in Harbour Porpoise Liver Tissue by HybridSPE<sup>®</sup>–UPLC<sup>®</sup>–MS/MS
by: Simone Trimmel, et al.
Published: (2021-08-01)

Identification of the Trace Components in BopuzongJian and <em>Macleaya cordata</em> Extract Using LC-MS Combined with a Screening Method
by: Zhuang Dong, et al.
Published: (2021-06-01)

Simultaneous Quantification of Ivacaftor, Tezacaftor, and Elexacaftor in Cystic Fibrosis Patients’ Plasma by a Novel LC–MS/MS Method
by: Federica Pigliasco, et al.
Published: (2023-02-01)

Carbamazepine and carbamazepine-epoxide concentrations in mothers, colostrum, and breastfed newborns: Comparison with concentrations determined during delivery and in the mature milk period
by: Ivana Kacirova, et al.
Published: (2022-07-01)

Therapeutic Drug Monitoring of Carbamazepine: A 20-Year Observational Study
by: Grzegorz Grześk, et al.
Published: (2021-11-01)

Method of simultaneous determination of carbamazepine and carbamazepine-10,11-epoxide by HPLC-MS/MS
by: T. A. Rodina, et al.
Published: (2018-02-01)

Glutamate-Evoked Ca<sup>2+</sup> Responses in the Rat Suprachiasmatic Nucleus: Involvement of Na<sup>+</sup>/K<sup>+</sup>-ATPase and Na<sup>+</sup>/Ca<sup>2+</sup>-Exchanger
by: Pi-Cheng Cheng, et al.
Published: (2023-03-01)

Heterotridentate Organomonophosphines in Pt(κ<sup>3</sup>–X<sup>1</sup>P<sup>1</sup>X<sup>2</sup>)(Y) (X<sup>1,2</sup> = N<sup>1,2</sup> or S<sup>1,2</sup>), Pt(κ<sup>3</sup>–P<sup>1</sup>N<sup>1</sup>X<sup>1</sup>)(Y) (X<sup>1</sup> = O, C, S or Se) Pt(κ<sup>3</sup>–P<sup>1</sup>S<sup>1</sup>Cl<sup>1</sup>)(Cl) and Pt(κ<sup>3</sup>–P<sup>1</sup>Si<sup>1</sup>N<sup>1</sup>)(OL)—Structural Aspects
by: Milan Melník, et al.
Published: (2022-12-01)

Na<sup>+</sup>,K<sup>+</sup>-ATPase with Disrupted Na<sup>+</sup> Binding Sites I and III Binds Na<sup>+</sup> with Increased Affinity at Site II and Undergoes Na<sup>+</sup>-Activated Phosphorylation with ATP
by: Hang N. Nielsen, et al.
Published: (2024-01-01)

Therapeutic drug monitoring and methods of quantitation for carbamazepine
by: Cristian Tuchila, et al.
Published: (2017-10-01)

Regulation of m<sup>6</sup>A Methylome in Cancer: Mechanisms, Implications, and Therapeutic Strategies
by: Poshan Yugal Bhattarai, et al.
Published: (2023-12-01)

ESI–LC–MS/MS for Therapeutic Drug Monitoring of Binary Mixture of Pregabalin and Tramadol: Human Plasma and Urine Applications
by: Atiah H. Almalki, et al.
Published: (2021-02-01)

A Fresh View on Limestone Calcined Clay Cement (LC<sup>3</sup>) Pastes
by: Hassan Ez-zaki, et al.
Published: (2021-06-01)

Optimized Therapeutic <sup>177</sup>Lu-Labeled PSMA-Targeted Ligands with Improved Pharmacokinetic Characteristics for Prostate Cancer
by: Yitian Wu, et al.
Published: (2022-12-01)

Organomonophosphines in Pt(η<sup>3</sup>-X<sup>1</sup>X<sup>2</sup>X<sup>3</sup>)(PR<sub>3</sub>), (X = N<sup>1</sup>, N<sup>2</sup>, N<sup>3</sup>; S<sup>1</sup>, S<sup>2</sup>, S<sup>3</sup>; or Te<sup>1</sup>, Te<sup>2</sup>, Te<sup>3</sup>) Derivatives: Structural Aspects
by: Milan Melník, et al.
Published: (2023-06-01)

The Pseudo-Protic Ionic Liquids TOAH<sup>+</sup>Cl<sup>−</sup> and TODAH<sup>+</sup>Cl<sup>−</sup> as Carriers for Facilitated Transport of In(III) from HCl Solutions
by: Francisco José Alguacil, et al.
Published: (2022-12-01)

Simultaneous LC-ESI-MS/MS Quantification of Levosimendan and Its Metabolites for Therapeutic Drug Monitoring of Cardiac Surgery Patients
by: Hannah Kipka, et al.
Published: (2022-07-01)

NanoUPLC-MS<sup>E</sup> proteomic data assessment of soybean seeds using the Uniprot database
by: Murad Andre M, et al.
Published: (2012-11-01)

Comparative Chemical Profiling and Monacolins Quantification in Red Yeast Rice Dietary Supplements by <sup>1</sup>H-NMR and UHPLC-DAD-MS
by: Rabab Hachem, et al.
Published: (2020-01-01)

Effects of Oregano Essential Oil on IgA<sup>+</sup>, IgG<sup>+</sup>, and IgM<sup>+</sup> Cells in the Jejunum of Castrated Holstein Bulls
by: Qiyan Liu, et al.
Published: (2023-12-01)

Therapeutic Potential of <sup>47</sup>Sc in Comparison to <sup>177</sup>Lu and <sup>90</sup>Y: Preclinical Investigations
by: Klaudia Siwowska, et al.
Published: (2019-08-01)

Comparison of Flow and Compression Properties of Four Lactose-Based Co-Processed Excipients: Cellactose<sup>®</sup> 80, CombiLac<sup>®</sup>, MicroceLac<sup>®</sup> 100, and StarLac<sup>®</sup>
by: Martin Dominik, et al.
Published: (2021-09-01)