Isoalantolactone inhibits pancreatic cancer proliferation by regulation of PI3K and Wnt signal pathway.

Isoalantolactone inhibits pancreatic cancer proliferation by regulation of PI3K and Wnt signal pathway.

<h4>Background/aims</h4>Isoalantolactone (IATL) is one of multiple isomeric sesquiterpene lactones and is isolated from inula helenium. IATL has multiple functions such as antibacterial, antihelminthic and antiproliferative activities. IATL also inhibits pancreatic cancer proliferation a...

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Bibliographic Details
Main Authors: Chaoxiong Zhang, Lei Huang, Jingyuan Xiong, Linshen Xie, Shi Ying, You Jia, Yuqin Yao, Xuejiao Song, Zhenguo Zeng, Jialing Yuan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0247752

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