Understanding Passive Membrane Permeation of Peptides: Physical Models and Sampling Methods Compared

The early characterization of drug membrane permeability is an important step in pharmaceutical developments to limit possible late failures in preclinical studies. This is particularly crucial for therapeutic peptides whose size generally prevents them from passively entering cells. However, a sequ...

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Bibliographic Details
Main Authors: Liuba Mazzanti, Tâp Ha-Duong
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/24/5/5021

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