Novel Nickel(II), Palladium(II), and Platinum(II) Complexes with <i>O</i>,<i>S</i> Bidendate Cinnamic Acid Ester Derivatives: An In Vitro Cytotoxic Comparison to Ruthenium(II) and Osmium(II) Analogues

Novel Nickel(II), Palladium(II), and Platinum(II) Complexes with <i>O</i>,<i>S</i> Bidendate Cinnamic Acid Ester Derivatives: An In Vitro Cytotoxic Comparison to Ruthenium(II) and Osmium(II) Analogues

(1) Background: Since the discovery of cisplatin’s cytotoxic properties, platinum(II) compounds have attracted much interest in the field of anticancer drug development. Over the last few years, classical structure–activity relationships (SAR) have been broken by some promising new compounds based o...

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Bibliographic Details
Main Authors: Jana Hildebrandt, Norman Häfner, Helmar Görls, Marie-Christin Barth, Matthias Dürst, Ingo B. Runnebaum, Wolfgang Weigand
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:International Journal of Molecular Sciences
Subjects:
metal-based compounds
cancer treatment
platinum resistance
ovarian cancer
Online Access:https://www.mdpi.com/1422-0067/23/12/6669

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