Silencing of Fused Toes Homolog (FTS) Increases Radiosensitivity to Carbon-Ion Through Downregulation of Notch Signaling in Cervical Cancer Cells

Silencing of Fused Toes Homolog (FTS) Increases Radiosensitivity to Carbon-Ion Through Downregulation of Notch Signaling in Cervical Cancer Cells

The effects of Carbon ion radiation (C-ion) alone or in combination with fused toes homolog (FTS) silencing on Notch signaling were investigated in uterine cervical cancer cell lines (ME180 and CaSki). In both cell lines, upon irradiation with C-ion, the expression of Notch signaling molecules (Notc...

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Bibliographic Details
Main Authors: Prabakaran D.S., Pankaj Kumar Chaturvedi, Takashi Shimokawa, Ki-Hwan Kim, Woo-Yoon Park
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Oncology
Subjects:
cervical cancer
fused toes homolog
notch
spheroid
carbon-ion beam
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.730607/full

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