Finding driver pathways in cancer: models and algorithms

Finding driver pathways in cancer: models and algorithms

<p>Abstract</p> <p>Background</p> <p>Cancer sequencing projects are now measuring somatic mutations in large numbers of cancer genomes. A key challenge in interpreting these data is to distinguish <it>driver mutations</it>, mutations important for cancer dev...

Full description

Bibliographic Details
Main Authors: Vandin Fabio, Upfal Eli, Raphael Benjamin J
Format: Article
Language:English
Published: BMC 2012-09-01
Series:Algorithms for Molecular Biology
Subjects:
Cancer
Somatic Mutations
Driver mutations
Pathways
Background mutation rate
Generative models
Online Access:http://www.almob.org/content/7/1/23

Similar Items

Similar Items