A Nonenzymatic Glucose Sensor Platform Based on Specific Recognition and Conductive Polymer-Decorated CuCo<sub>2</sub>O<sub>4</sub> Carbon Nanofibers
CuCo<sub>2</sub>O<sub>4</sub> decoration carbon nanofibers (CNFs) as an enzyme-free glucose sensor were fabricated via electrospinning technology and carbonization treatment. The CNFs with advantages of abundant nitrogen amounts, porosity, large surface area, and superior ele...
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| Format: | Article |
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MDPI AG
2020-06-01
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| Series: | Materials |
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| Online Access: | https://www.mdpi.com/1996-1944/13/12/2874 |
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| author | Yongling Ding Huadong Sun Chunrong Ren Mingchen Zhang Kangning Sun |
| author_facet | Yongling Ding Huadong Sun Chunrong Ren Mingchen Zhang Kangning Sun |
| author_sort | Yongling Ding |
| collection | DOAJ |
| description | CuCo<sub>2</sub>O<sub>4</sub> decoration carbon nanofibers (CNFs) as an enzyme-free glucose sensor were fabricated via electrospinning technology and carbonization treatment. The CNFs with advantages of abundant nitrogen amounts, porosity, large surface area, and superior electrical conductivity were used as an ideal matrix for CuCo<sub>2</sub>O<sub>4</sub> decoration. The resultant CuCo<sub>2</sub>O<sub>4</sub>–CNF hybrids possessed favorable properties of unique three-dimensional architecture and good crystallinity, accompanied by the CuCo<sub>2</sub>O<sub>4</sub> nanoparticles uniformly growing on the CNF skeleton. To further enhance the selective molecular recognition capacity of the developed sensor, a conductive film was synthesized through the electropolymerization of thiophene and thiophene-3-boronic acid (TBA). Based on the synergistic effects of the performances of CNFs, CuCo<sub>2</sub>O<sub>4</sub> nanoparticles, and boronic acid-decorated polythiophene layer, the obtained poly(thiophene-3-boronic acid) (PTBA)/CuCo<sub>2</sub>O<sub>4</sub>–CNF-modified electrodes (PTBA/CuCo<sub>2</sub>O<sub>4</sub>–CNFs/glassy carbon electrode (GCE)) displayed prominent electrocatalytic activity toward electro-oxidation of glucose. The fabricated sensor presented an outstanding performance in the two linear ranges of 0.01–0.5 mM and 0.5–1.5 mM, with high selectivity of 2932 and 708 μA·mM<sup>−1</sup>·cm<sup>−2</sup>, respectively. The composite nanofibers also possessed good stability, repeatability, and excellent anti-interference selectivity toward the common interferences. All these results demonstrate that the proposed composite nanofibers hold great potential in the application of constructing an enzyme-free glucose sensing platform. |
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| issn | 1996-1944 |
| language | English |
| last_indexed | 2024-03-10T18:51:40Z |
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| series | Materials |
| spelling | doaj.art-b49f6569056042129c422fd4002687062023-11-20T05:04:51ZengMDPI AGMaterials1996-19442020-06-011312287410.3390/ma13122874A Nonenzymatic Glucose Sensor Platform Based on Specific Recognition and Conductive Polymer-Decorated CuCo<sub>2</sub>O<sub>4</sub> Carbon NanofibersYongling Ding0Huadong Sun1Chunrong Ren2Mingchen Zhang3Kangning Sun4School of Transportation Civil Engineering, Shandong Jiaotong University, Jinan 250357, ChinaSchool of Transportation Civil Engineering, Shandong Jiaotong University, Jinan 250357, ChinaSchool of Transportation Civil Engineering, Shandong Jiaotong University, Jinan 250357, ChinaPostdoctoral Technology Research Center, Shandong Anran Group, Weihai 264205, ChinaSchool of Materials Science and Engineering, Shandong University, Jinan 250002, ChinaCuCo<sub>2</sub>O<sub>4</sub> decoration carbon nanofibers (CNFs) as an enzyme-free glucose sensor were fabricated via electrospinning technology and carbonization treatment. The CNFs with advantages of abundant nitrogen amounts, porosity, large surface area, and superior electrical conductivity were used as an ideal matrix for CuCo<sub>2</sub>O<sub>4</sub> decoration. The resultant CuCo<sub>2</sub>O<sub>4</sub>–CNF hybrids possessed favorable properties of unique three-dimensional architecture and good crystallinity, accompanied by the CuCo<sub>2</sub>O<sub>4</sub> nanoparticles uniformly growing on the CNF skeleton. To further enhance the selective molecular recognition capacity of the developed sensor, a conductive film was synthesized through the electropolymerization of thiophene and thiophene-3-boronic acid (TBA). Based on the synergistic effects of the performances of CNFs, CuCo<sub>2</sub>O<sub>4</sub> nanoparticles, and boronic acid-decorated polythiophene layer, the obtained poly(thiophene-3-boronic acid) (PTBA)/CuCo<sub>2</sub>O<sub>4</sub>–CNF-modified electrodes (PTBA/CuCo<sub>2</sub>O<sub>4</sub>–CNFs/glassy carbon electrode (GCE)) displayed prominent electrocatalytic activity toward electro-oxidation of glucose. The fabricated sensor presented an outstanding performance in the two linear ranges of 0.01–0.5 mM and 0.5–1.5 mM, with high selectivity of 2932 and 708 μA·mM<sup>−1</sup>·cm<sup>−2</sup>, respectively. The composite nanofibers also possessed good stability, repeatability, and excellent anti-interference selectivity toward the common interferences. All these results demonstrate that the proposed composite nanofibers hold great potential in the application of constructing an enzyme-free glucose sensing platform.https://www.mdpi.com/1996-1944/13/12/2874electrospinningCuCo<sub>2</sub>O<sub>4</sub>thiophene-3-boronic acidelectrocatalytic activityglucose sensor |
| spellingShingle | Yongling Ding Huadong Sun Chunrong Ren Mingchen Zhang Kangning Sun A Nonenzymatic Glucose Sensor Platform Based on Specific Recognition and Conductive Polymer-Decorated CuCo<sub>2</sub>O<sub>4</sub> Carbon Nanofibers Materials electrospinning CuCo<sub>2</sub>O<sub>4</sub> thiophene-3-boronic acid electrocatalytic activity glucose sensor |
| title | A Nonenzymatic Glucose Sensor Platform Based on Specific Recognition and Conductive Polymer-Decorated CuCo<sub>2</sub>O<sub>4</sub> Carbon Nanofibers |
| title_full | A Nonenzymatic Glucose Sensor Platform Based on Specific Recognition and Conductive Polymer-Decorated CuCo<sub>2</sub>O<sub>4</sub> Carbon Nanofibers |
| title_fullStr | A Nonenzymatic Glucose Sensor Platform Based on Specific Recognition and Conductive Polymer-Decorated CuCo<sub>2</sub>O<sub>4</sub> Carbon Nanofibers |
| title_full_unstemmed | A Nonenzymatic Glucose Sensor Platform Based on Specific Recognition and Conductive Polymer-Decorated CuCo<sub>2</sub>O<sub>4</sub> Carbon Nanofibers |
| title_short | A Nonenzymatic Glucose Sensor Platform Based on Specific Recognition and Conductive Polymer-Decorated CuCo<sub>2</sub>O<sub>4</sub> Carbon Nanofibers |
| title_sort | nonenzymatic glucose sensor platform based on specific recognition and conductive polymer decorated cuco sub 2 sub o sub 4 sub carbon nanofibers |
| topic | electrospinning CuCo<sub>2</sub>O<sub>4</sub> thiophene-3-boronic acid electrocatalytic activity glucose sensor |
| url | https://www.mdpi.com/1996-1944/13/12/2874 |
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