Features of intestinal microbiota disorders in the development of metabolic disorders in non-alcoholic fatty liver disease

We discussed about the term intestinal permeability like as the mucosal barrier a single structural and functional conception that includes the layer of mucus, the indigenous microbiota and the epithelium of the mucosa in this publication. Information was presented about the role of the microbiota,...

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Bibliographic Details
Main Authors: M. A. Livzan, T. S. Krolevets, S. I. Mozgovoy, N. A. Nikolaev, A. V. Nelidova
Format: Article
Language:Russian
Published: "Consilium Medicum" Publishing house 2021-02-01
Series:Терапевтический архив
Subjects:
Online Access:https://ter-arkhiv.ru/0040-3660/article/viewFile/64775/47651
Description
Summary:We discussed about the term intestinal permeability like as the mucosal barrier a single structural and functional conception that includes the layer of mucus, the indigenous microbiota and the epithelium of the mucosa in this publication. Information was presented about the role of the microbiota, the composition of intestinal mucus, epithelial cells and proteins of tight junctions which lead to various metabolic diseases. The complex pathogenetic interactions are formed between the intestinal mucosal barrier, metabolic disorders such as non-alcoholic fatty liver disease and cardiovascular diseases. The complex researches and modification of this interactions will allow to create personalized approaches and to prevent of these diseases.
ISSN:0040-3660
2309-5342