The Role of Sulforaphane in Epigenetic Mechanisms, Including Interdependence between Histone Modification and DNA Methylation

The Role of Sulforaphane in Epigenetic Mechanisms, Including Interdependence between Histone Modification and DNA Methylation

Carcinogenesis as well as cancer progression result from genetic and epigenetic changes of the genome that leads to dysregulation of transcriptional activity of genes. Epigenetic mechanisms in cancer cells comprise (i) post-translation histone modification (i.e., deacetylation and methylation); (ii)...

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Bibliographic Details
Main Authors: Agnieszka Kaufman-Szymczyk, Grzegorz Majewski, Katarzyna Lubecka-Pietruszewska, Krystyna Fabianowska-Majewska
Format: Article
Language:English
Published: MDPI AG 2015-12-01
Series:International Journal of Molecular Sciences
Subjects:
cruciferous vegetables
isothiocyanates
sulforaphane
epigenetic cancer chemoprevention
Online Access:http://www.mdpi.com/1422-0067/16/12/26195

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